Monday 20 October 2014

Treatment of Chickenpox, Shingles and Genital Herpes using Generic Zovirax Tablets

What is Chickenpox?

Chickenpox (varicella) is a common illness caused by the varicella-zoster virus. Most cases are in children under age 15, causes an itchy rash and red spots or blisters (pox) all over the body. It is most common in children, but most people will get chickenpox at some point in their lives if they have not had the chickenpox vaccine. It spreads very easily from one person to another through coughing or sneezing of sick individuals or through direct contact with secretions from the rash. A person with chickenpox is infectious one to two days before the rash appears.
After you have had chickenpox, you are not likely to get it again. But the virus stays in your body long after you get over the illness. If the virus becomes active again, it can cause a painful viral infection called a style="text-decoration:underline;color:#FF3300;" href="http://en.wikipedia.org/wiki/Herpes_zoster">shingles.

Generic Zovirax – Product Information

Generic Zovirax is used for the treatment of chickenpox (varicella) and for the acute treatment of herpes zoster (shingles). It is also used for the for the treatment of initial episodes and the management of recurrent episodes of Genital Herpes.
The active ingredient present in Generic Zovirax is Aciclovir (or Acyclovir). Aciclovir is marketed under trade names such as Cyclovir, Herpex, Acivir, Acivirax, Zovirax, Zoral, and Xovir. It is one of the most commonly used antiviral drugs, it is primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of varicella zoster (chickenpox) and herpes zoster (shingles). Zovirax tablets are manufactured by GlaxoSmithKline (GSK) India and Generic Zovirax (Acivir Tablets) are manufactured by Cipla Ltd., India.

Generic Zovirax - Contraindications

Generic Zovirax is contraindicated in patients that have a hypersensitivity to Acyclovir or Valacyclovir or any inactive ingredient present in the product.

Generic Zovirax Tablets - Dosage

Zovirax (Aciclovir) comes as an oral tablet in 125 mg, 200 mg, 400 mg, and 800 mg dosage forms. Among other side effects, Generic Zovirax Tablets (Aciclovir) may cause an upset stomach. The recommended adult Oral dosage of Generic Zovirax for adults is given below:
Dosage for Treatment of Herpes Simplex (Cold Sores) in Adults
For treatment of Herpes Simplex infections (Cold Sores or Fever Blisters), 200 mg Generic Zovirax should be taken five times daily at approximately four-hourly intervals, omitting the night-time dose. Treatment should continue for 5 days but in severe initial infections may have to be extended. In severely immune-compromised patients (e.g. after marrow transplants) or in patients with impaired absorption from the gut, the dose can be doubled to 400 mg or alternatively intravenous dosing could be considered. Dosing should begin as early as possible after the start of an infection. For recurrent episodes this should preferably be during the prodromal period or when lesions first appear.

Dosage for Suppression of Herpes Simplex in Adults
For suppression of Herpes Simplex infections in immune-competent patients, 200mg Generic Zovirax should be taken four times daily at approximately six-hourly intervals. Many patients may be conveniently managed on a regimen of 400 mg Generic Zovirax taken twice daily at approximately twelve-hourly intervals. Dosage titration down to 200 mg Generic Zovirax taken thrice daily at approximately eight-hourly intervals or even twice daily at approximately twelve-hourly intervals, may prove effective. Some patients may experience breakthrough infections on total daily doses of 800 mg Generic Zovirax. Therapy should be interrupted periodically at intervals of six to twelve months in order to observe possible changes in the natural history of the disease.

Dosage for Prophylaxis of Herpes Simplex in Adults
For prophylaxis of Herpes Simplex infections in immune-compromised patients, 200 mg Generic Zovirax should be taken four times daily at approximately six-hourly intervals.

Dosage for Treatment of Herpes Zoster (Shingles) in Adults
For treatment of Herpes Zosterinfections (Shingles), 800 mg Generic Zovirax should be taken five times daily at approximately four-hourly intervals, omitting the night-time dose. Treatment should continue for seven days.

Dosage for Treatment of Genital Herpes in Adults:
Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. Alternative regimens have included doses ranging from 200 mg 3 times daily to 200 mg 5 times daily.

Treatment of Chickenpox:
Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for five days. Children over 40 kg should receive the adult dose for chickenpox. Adults and Children over 40 kg: 800 mg 4 times daily for five days.

Side Effects of Generic Zovirax

The most common side effects reported in patients treated with Generic Zovirax include Headache, dizziness, Nausea, vomiting, diarrhoea, abdominal pains, Pruritus, rashes(including photosensitivity), Fatigue, fever.
The uncommon side effects include Urticaria, accelerated diffuse hair loss. Anaphylaxis, Dyspnoea, Reversible rises in bilirubin and liver related enzymes, Angioedema and Increases in blood urea and creatinine are among the rare side effects.
The extremely rare side effects include Acute renal failure, renal pain, Hepatitis, jaundice, Agitation, confusion, tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, convulsions, somnolence, encephalopathy, coma Anaemia, leukopenia and thrombocytopenia.

Generic Zovirax Tablets - More Details

For more details on Generic Zovirax tablets please watch the presentation below:

Saturday 18 October 2014

Blood clot prevention using Generic Plavix Tablets

Generic Plavix Tablets - Product Information

Generic Plavix (Clopidogrel Bisulfate) is a platelet inhibitor and prevent blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It used to treat patients with Acute coronary syndrome (unstable angina (UA)/non-ST-segment elevation ACS (NSTEMI)& ST-elevation myocardial infarction (STEMI) ), recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease. The active ingredient present in Generic Plavix (Clopivas Tablets) is Clopidogrel Bisulfate

Generic Forms and Brand names of Clopidogrel (Generic Plavix)

Generic Plavix is available as Clopivas manufactured by Cipla Ltd., India. Generic Plavix which has the active ingredient Clopidogrel Bisulfate is also sold as Plagril as well as other brand names.

Mechanism of Action

Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets.

Generic Plavix - Contraindications

Generic Plavix (Clopivas Tablets) is contraindicated in patients with a hypersensitivity to Clopidogrel Bisulfate or any inactive component of this medication.
It is also contraindicated in patients with active pathological bleeding, such as peptic ulcer or intracranial hemorrhage.

Generic Plavix - Side Effects

Bleeding, including life-threatening and fatal bleeding, is the most commonly reported side effect of Generic Plavix (Clopivas Tablets).
Thrombotic thrombocytopenic purpura (TTP), sometimes fatal, has been reported following use of Generic Plavix, sometimes after a short duration.

Pregnancy and Nursing

Generic Plavix should be used during pregnancy only if clearly needed. Nursing mothers have to either discontinue Clopivas (Generic Plavix) or nursing, taking into consideration importance of drug to mother.

Overdosage

Platelet inhibition by Generic Plavix is irreversible and will last for the life of the platelet. Overdose following clopidogrel administration may result in bleeding complications. Platelet transfusion may restore clotting ability.

Friday 17 October 2014

Treatment of Moderate to Severe Acne Using Generic Accutane Capsules

What is Acne?

Acne vulgaris (cystic acne or simply acne) is a human skin condition characterized by areas of skin with intense erythema, inflammation, seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules), cysts, and possibly scarring.
Acne affects mostly skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Severe acne is inflammatory, but acne can also manifest in noninflammatory forms. The lesions are caused by changes in pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland, changes that require androgen stimulation.
Some of the large nodules were previously called "cysts" and the term nodulocystic has been used to describe severe cases of inflammatory acne. Oral antibacterials, were initially used as the first line therapy for severe nodular acne. However due to concerns of antibacterial adverse effects, patient adherence, and antimicrobial resistance the search for alternate therapies started and finally Isotretinoin, an oral retinoid was introduced in 1982.
Oral antibacterials are still used as an alternative for patients with severe acne who have a hypersensitivity towards oral retinoids, or for whom the use of retinoids is contraindicated.

Generic Accutane (Isotretinoin) – Product Information

Generic Accutane Capsules (Isotroin), an extremely powerful and potent acne-controlling medicine, is used to treat severe recalcitrant nodular acne that has failed other therapy. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. "Severe," by definition, means "many" as opposed to "few or several" nodules.
A single course of therapy for 15 to 20 weeks has been shown to result in complete and prolonged remission of disease in many patients. If a second course of therapy is needed, it should not be initiated until at least 8 weeks after completion of the first course.
Isotretinoin is available as Roaccutane, Isotroin, Tretiva, Amnesteem, Claravis, and Sotret. Earlier it was available as Accutane in the US market.

Generic Accutane (Isotretinoin Capsules) - Contraindications

Generic Accutane Capsules are contraindicated in patients that have a hypersensitivity to Isotretinoin or any inactive component of this medication. They are also contraindicated in the following cases:
Generic Accutane should not be given to female patients that are pregnant.

Generic Accutane (Isotroin Capsules) - Dosage

The recommended adult Oral dosage of Generic Accutane (Isotroin Capsules) is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks.
Accutane should always be administered with a meal. Failure to take Accutane with food will significantly decrease absorption.

Side Effects of Generic Accutane (Isotroin Capsules)

The side effects reported in patients treated with Generic Accutane capsules are Anemia, Increased red blood cell sedimentation rate, Thrombocytopenia, Thrombocytosis, Neutropenia, Headache, Blepharitis, Conjunctivitis, Dry eyes, Eye irritation, Epistaxis, Nasal dryness, Nasopharyngitis, Increased transaminase, Cheilitis, Dermatitis, Dry skin, Localised exfoliation, Pruritus, Rash, Erythematous, Skin fragility, Arthralgia, Myalgia, Back pain, Increased triglycerides, Decreased HDL, Increased blood cholesterol, Increased blood glucose, Haematuria, and Proteinuria.

Generic Accutane Capsules - More Details

For more details please read the Prescription Information or watch the presentation below:

Thursday 16 October 2014

Treatment of Hypertension and Angina Pectoris with Generic Norvasc Tablets

What is Hypertension?

Hypertension (HTN) or high blood pressure, sometimes called arterial hypertension, is a chronic medical condition which is characterised by elevated blood pressure in the arteries. As a result of this, the heart to work harder than normal to circulate blood through the blood vessels.
Blood pressure, which is a measurement of the force against the walls of your arteries as your heart pumps blood through your body, is summarised by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole). Normal blood pressure at rest is within the range of 100-140mmHg systolic (top reading) and 60-90mmHg diastolic (bottom reading).
High blood pressure is said to be present if it is persistently at or above 140/90 mmHg. Hypertension is a major risk factor for stroke, myocardial infarction (heart attacks), heart failure, aneurysms of the arteries (e.g. aortic aneurysm), peripheral arterial disease and is a cause of chronic kidney disease.

What is Angina Pectoris ?

Angina, or Angina Pectoris is a pain or discomfort that keeps coming back when part of your heart does not get enough blood and thus a lack of oxygen supply and waste removal. Angina feels like a pressing or squeezing pain, usually in your chest under the breastbone. Sometimes you can feel it in your shoulders, arms, neck, jaws, or back. Generic Norvasc can relieve this pain.
Angina pectoris, commonly known as angina, is chest pain due to ischemia (a lack of blood, thus a lack of oxygen supply and waste removal) of the heart muscle, generally due to obstruction or spasm of the coronary arteries (the heart's blood vessels). Coronary artery disease, the main cause of angina, is due to hardening of the coronary arteries (atherosclerosis). Treatments for angina include lifestyle changes, medicines, medical procedures, cardiac rehabilitation (rehab), and other therapies.

Generic Norvasc (Amlopres Tablets) – Product Information

Generic Norvasc (Amlopres Tablets) is a type of medication known as a calcium channel blocker (CCB). It is used to treat high blood pressure (hypertension) and a type of chest pain called angina pectoris. It can be used by itself or with other medicines to treat these conditions.

Generic Norvasc - Active Ingredient

The active ingredient present in Generic Norvasc is Amlodipine Besylate (Besilate)

Generic Norvasc - Contraindications

Generic Norvasc (Amlopres Tablets) is contraindicated in patients that have hypersensitivity to amlodipine, dihydropyridines or any inactive component of this medicine.

Generic Norvasc (Amlopres Tablets) - Dosage

Swallow Amlopres tablet whole with a full glass of water. Take your medicine at about the same time each day, either morning or evening. Taking it at the same time each day will have the best effect. Generic Norvasc can be taken with or without food.
For both hypertension and angina, the recommended initial dose is 5 mg Generic Norvasc once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily.

Side Effects of Generic Norvasc

Most side effects are mild or moderate. Tell your doctor or pharmacist if you experience any of the following common side effects of Norvasc and they worry you. The most frequently occurring side effects of Generic Norvasc (Amlopres Tablets) include swelling of the ankles, feet, face or hands, headache, dizziness, flushing, fast or irregular heart beats, tiredness, drowsiness or sleepiness, stomach pain or nausea.
Tell your doctor immediately if you notice any of the following: changes in heart beat either fast or slow chest pain chest pain associated with exertion (angina) that lasts longer, is more severe or occurs more often dizziness or lightheadedness on standing up from a sitting or lying position, eye pain or change in vision changes in mood, feeling anxious or nervous symptoms of liver disease such as itching, yellowing of the skin and eyes, and dark coloured urine.These may be serious side effects that may need urgent medical attention. Serious side effects are rare.
Inform your doctor immediately or go to Accident and Emergency at your nearest hospital, if you notice any of the following serious side effects of Generic Norvasc Tablets: shortness of breath, symptoms of allergy such as skin rash and/or itching severe upper stomach pain, often with nausea and vomiting.

Generic Generic Norvasc Tablets - More Details

For more details please read the Prescribing Information or watch the presentation below:

Wednesday 15 October 2014

Treatment of Schizophrenia, Bipolar I disorder and Major depressive disorder using Generic Abilify Tablets

Generic Abilify Tablets – Product Information

Generic Abilify which is used to treat schizophrenia, Bipolar I disorder and major depressive disorder is available as Asprito Tablets.
Asprito Tablets (Aripiprazole Tablets) manufactured by Intas Pharmaceuticals Ltd., India is approved by the Indian FDA. In addition , the active ingredient Aripiprazole is approved by the US FDA.

Generic Abilify Tablets - Contraindications

Generic Abilify tablets is contraindicated for patients with a hypersensitivity to aripiprazole or any other ingredient present in Generic Abilify tablets . Hypersensitive reactions have ranged from pruritus/urticaria to anaphylaxis.

Generic Abilify Tablets - Dosage

The recommended adult Oral dosage of Generic for adults is given below:
The recommended dosage for the treatment of Schizophrenia in adults is 10-15 mg/day with an initial dosage of 10-15 mg/day and a maximum of 30 mg/day.
For Bipolar mania in adults: In case of Generic Abilify Monotherapy the initial dosage is 15 mg/day, the recommended dosage is 15 mg/day and the maximum dosage 30 mg/day. In case Generic Abilify tablets are used as an adjunct to lithium or valproate the initial dose is 10-15 mg/day, the recommended dose is 15 mg/day with the maximum dose being 30 mg/day
The recommended dosage of Aripiprazole Tablets for the treatment of major depressive disorder in adults as an adjunct to antidepressants is 5-10 mg/day with the starting dose as 2-5 mg/day and the maximum dose being 15 mg/day.

Side Effects of Abilify Tablets

The most common side effects reported in patients treated with with an incidence rate of 5% or more and at least twice that for placebo:
Adult patients with schizophrenia: akathisia
Adult patients (monotherapy) with bipolar mania: akathisia, sedation, restlessness, tremor, and extrapyramidal disorder
Adult patients (adjunctive therapy with lithium or valproate) with bipolar mania: akathisia, insomnia, and extrapyramidal disorder
Adult patients with major depressive disorder (adjunctive treatment to antidepressant therapy): akathisia, restlessness, insomnia, constipation, fatigue and blurred vision
Adult patients with agitation associated with schizophrenia or bipolar mania: nausea

Generic Abilify Tablets - More Details

For more details on Generic please read the Prescription Information or watch the presentation below:

Tuesday 14 October 2014

Treatment of Osteoporosis and Paget's Disease using Generic Fosamax Tablets

What is osteoporosis?

Osteoporosis is a disease of bones which causes bones to become more porous, gradually making them weaker, more brittle and leads to an increased risk of fracture. Osteoporosis is common in postmenopausal women and also may occur in men. Osteoporosis often occurs in women several years after, the menopause, which occurs when the ovaries virtually stop producing the female hormone, oestrogen, or are removed (which may occur, for example, at the time of a hysterectomy). The earlier a woman reaches the menopause, the greater the risk of osteoporosis.
As many as half of all women and a quarter of men older than 50 will break a bone due to osteoporosis.
In osteoporosis, the bone mineral density (BMD) is reduced, bone microarchitecture deteriorates, and the amount and variety of proteins in bone are altered. Although Osteoporosis itself has no symptoms, its main consequence is the increased risk of bone fractures. Osteoporotic fractures occur in situations where healthy people would not normally break a bone; they are therefore regarded as fragility fractures.

What is Paget's Disease?

Paget's disease of bone is a disease that can result in enlarged and misshapen bones. In people with Paget's disease, there is excessive breakdown of bone tissue, and formation of new bone tissue causing the affected bone to weaken, resulting in pain, misshapen bones, fractures, and arthritis in the joints near the affected bones.
Paget's disease typically is localized, affecting just one or a few bones, as opposed to osteoporosis, for example, which usually affects all the bones in the body. It often involves bones of the arms, collarbones, leg, pelvis, spine, and skull.The disease occurs worldwide, but is more common in Europe, Australia, and New Zealand.

Generic Fosamax (Osteofos Tablets) – Product Information

Generic Fosamax (Osteofos Tablets) is used to prevent osteoporosis in postmenopausal women, and to treat Paget's disease of the bone. Generic Fosamax is also used to treat or prevent osteoporosis in men, premenopausal women and postmenopausal women using oestrogen who are receiving corticosteroid medicines, such as prednisone and dexamethasone.

Generic Fosamax Tablets - Contraindications

Generic Fosamax (Osteofos Tablets) are contraindicated in patients that have a hypersensitivity to Alendronate Sodium tor any inactive component of this medication. They are also contraindicated in patients that have Hypocalcaemia or abnormalities of the oesophagus which delay oesophageal emptying such as stricture or achalasia.
Osteofos Tablets should not be administered to patients that are unable to stand or sit upright for at least 30 minutes.

Generic Fosamax (Osteofos Tablets) - Dosage

Generic Fosamax must be taken at least one half hour before the first food, beverage, or medication of the day with plain water only. To reduce the chances of oesophageal irritation, Generic Fosamax should only be swallowed upon arising for the day with a full glass of water and patients should not lie down for at least 30 minutes and until after their first food of the day. The recommended dosage of for various indications is given below:
Treatment of Osteoporosis in Postmenopausal Women and in Men :
The recommended dosage is one 70 mg tablet once weekly.
Prevention of Osteoporosis in Postmenopausal Women:
The recommended dosage is 5 mg once a day.
Treatment and Prevention of Glucocorticoid-Induced Osteoporosis in Men, Premenopausal Women and Postmenopausal Women Receiving Oestrogen :
The recommended dosage is 5 mg once a day.
Paget's Disease of Bone in men and women : The recommended treatment regimen is 40 mg once a day for six months.

Side Effects of Generic Fosamax Tablets

The following upper gastrointestinal side effects were reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: abdominal pain, dyspepsia, oesophageal ulcer, dysphagia and abdominal distention. Rarely, rash and erythema have occurred. Additionally, the following side effects were also reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: musculoskeletal (bone, muscle or joint) pain, constipation, diarrhoea, flatulence, and headache.

Generic Fosamax Tablets - More Details

For more details please watch the presentation below:

Monday 13 October 2014

Generic Cipro for Treatment of Bacterial Infections

Generic Cipro (Ciplox Tablets) - Product Information

The active ingredient present in Generic Cipro (Ciplox Tablets) is ciprofloxacin hydrochloride. Ciplox Tablets are available in strengths of 100 mg, 250 mg, 500 mg and 750 mg. Generic Cipro (Ciplox Tablets) are used to treat infections caused by susceptible bacteria.

Uses of Generic Cipro (Ciplox Tablets)

Generic Cipro (Ciplox Tablets) - Dosage

Ciplox Tablets (Ciprofloxacin Hydrochloride) Dosage Ciplox tablets should be swallowed whole with adequate amount of liquid. Ciplox tablets can be taken with or without regard to meals. Fluids should be taken liberally. Antacids should not be taken concomitantly or within two hours of dosing. The adult dosage for various indications is given below: Respiratory tract, bone and joint infections:
Mild/moderate 500 mg twice daily/or 1000 mg once daily
Severe/complicated 750 mg twice daily
Urinary tract infections:
Acute uncomplicated 500 mg once daily for 3 days
Mild/moderate 250 mg twice daily / 500 mg once daily
Severe/complicated 500 mg twice daily/or 1000 mg once daily
Infectious diarrhoea:
Mild/moderate/severe 500 mg twice daily/or 1000 mg once daily
Gonorrhoea 250 mg single dose
Non-gonococcal urethritis 750 mg twice daily
Chancroid 500 mg twice daily/1000 mg once daily
Other infections 500-750 mg twice daily
Chronic Bacterial prostatitis:
1000 mg once daily for 28 days

Overdose Symptoms and Treatment

In the event of acute overdosage, reversible renal toxicity has been reported in certain cases. The stomach should be emptied by inducing vomiting or by gastric lavage. The patient should be carefully monitored and given supportive treatment, including monitoring of renal function and administration of magnesium, aluminum, or calcium containing antacids which can reduce the absorption of ciprofloxacin. Adeguate hydration must be maintained. Only a small amount of ciprofloxacin (< 10%) is removed from the body after hemodialysis or peritoneal dialysis.

Side Effects

The common side effects of Generic Cipro are Diarrhoea, vomiting, abdominal pain, headache, restlessness and rash

Generic Cipro - More Details

For more details please watch the presentation below:

Friday 10 October 2014

Treatment of Depression Using Generic Pamelor

What is Depression?

According to MediLexicon's Medical Dictionary, depression is "a mental state or chronic mental disorder characterized by feelings of sadness, loneliness, despair, low self-esteem, and self-reproach; accompanying signs include psychomotor retardation (or less frequently agitation), withdrawal from social contact, and vegetative states such as loss of appetite and insomnia."
Depressed people may feel sad, anxious, empty, hopeless, worried, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable; experience loss of appetite or overeating, have problems concentrating, remembering details, or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.
There are several types of depression(depressive disorders). Among the common types of depression are Major Depressive Disorder (major depression) and Dysthymic Disorder (dysthymia). Other types of depression include Psychotic depression, Postpartum depression (postnatal depression), SAD (seasonal affective disorder) and Bipolar disorder (manic-depressive illness).

Generic Pamelor – Product Information

Generic Pamelor (Primox Tablets / Sensival Tablets) is used for the relief of symptoms of depression. Nortriptyline Hydrochloride is also used for the treatment of nicotine dependence as an aid to smoking cessation.
Depression is thought to be caused by a chemical imbalance in parts of the brain. This affects your whole body and can cause emotional and physical symptoms such as feeling low in spirit, loss of interest in activities, being unable to enjoy life, poor appetite or overeating, disturbed sleep, often waking up early, loss of sex drive, lack of energy and feeling guilty over nothing. Generic Pamelor works by correcting this chemical imbalance and helps relieve the symptoms of depression.

Generic Pamelor - Active Ingredient

The active ingredient present in Generic Pamelor is Nortriptyline Hydrochloride.

Generic Pamelor - Contraindications

Generic Pamelor (Nortriptyline Hydrochloride) is contraindicated in the following situations:

  • Patients hypersensitive to nortriptyline hydrochloride or any inactive ingredient in the product should not be given the medication.
  • Cross-sensitivity between nortriptyline hydrochloride and other dibenzazepines is a possibility.
  • Nortriptyline is contraindicated for the treatment of nocturnal enuresis.
  • Nortriptyline Hydrochloride is contraindicated during the acute recovery period after myocardial infarction.
  • The concurrent use of nortriptyline hydrochloride or other tricyclic antidepressants with a monoamine oxidase inhibitor (MAOI) is contraindicated. It is advisable to discontinue the MAOI for at least 2 weeks before treatment with nortriptyline hydrochloride is started.
  • Nortriptyline is contraindicated for the treatment of depression in patients 12 years of age and under.

Generic Pamelor - Dosage

For the Relief of Symptoms of Depression:
Usual Adult Dose:
25 mg 3 or 4 times daily; dosage should begin at a low level and be increased as required.Doses above 100 mg per day are not recommended.
Elderly Patients:
25 mg to 50 mg per day, in divided doses.
Adolescent Depression:
Not recommended for use in adolescent patients 13-18 years of age for the treatment of depression, unless under the supervision of a specialist.
As an Aid in Smoking Cessation:
Nortriptyline hydrochloride is administered orally in the form of tablets. Commence dosing prior to quit date at 25 mg/day and then increase to 75 – 100mg when feasible over 10 days – 5 weeks. The recommended starting time is 10 – 28 days prior to the quit date and gradually increase to achieve a maintenance dose of 75 – 100 mg/day when possible for a total of up to 12 weeks.

Side Effects of Generic Pamelor

The common side effects of Generic Pamelor tablets are Stomach or bowel problems (e.g. nausea, diarrhoea, constipation), Dry mouth or taste change, Change in appetite, Shakiness or tremor, Trouble sleeping, Dizziness or light-headedness (especially on standing rapidly), Tingling or numbness of the hands or feet, Ringing or other persistent noise in the ears, and Difficulty in passing urine.
Inform your doctor as soon as possible if you notice any of the following as these side effects may be serious: Changes in the speed of your heart rate (increase or decrease), irregular heart beat, Agitation, anxiety, worsening of depression, Confusion or hallucinations (seeing or hearing things that are not there), Vision problems and Yellowing of the eyes or skin (jaundice).The above side effects are rare.
Inform your doctor immediately or go to accident and emergency at your nearest hospital if you notice any of the following very serious side effects:Symptoms of an allergic reaction (symptoms include: swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing), Severe chest pain or tightness, Thoughts of suicide, Fainting, seizures or fits. You may need urgent medical attention or hospitalisation. These side effects are very rare.

Generic Pamelor - More Details

For more details please watch the presentation below:

Thursday 9 October 2014

Treatment of Obesity using Generic Xenical Capsules

What is Obesity?

Obesity is a medical condition which is characterised by accumulatation of excess body fat has to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems. People are considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight in kilograms by the square of the person's height in metres, exceeds 30 kg/m2. In other words, a person is considered obese when his or her weight is 20% or more above normal weight.
Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity is most commonly caused by a combination of excessive food energy intake, lack of physical activity, and genetic susceptibility, although a few cases are caused primarily by genes, endocrine disorders, medications or psychiatric illness.

Generic Xenical Capsules (Orlimac Capsules) – Product Information

Generic Xenical (Orlimac Capsules) is a medicine used for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Generic Xenical is also used to reduce the risk for weight regain after prior weight loss.
The active ingredient present in Generic Xenical capsules is Orlistat. Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

Generic Xenical (Orlimac Capsules) - Contraindications

Generic Xenical (Orlimac Capsules) is contraindicated in patients with

  • A known hypersensitivity to Orlistat or to any component of this medication
  • Pregnancy
  • Patients with chronic malabsorption syndrome
  • Patients with cholestasis

Generic Xenical (Orlimac Capsules) - Dosage

The recommended adult Oral dosage of Generic Xenical (Orlistat Capsules) is one 120 mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal).
The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. If a meal is occasionally missed or contains no fat, the dose of Generic Xenical can be omitted. Patients should take a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat and distribute the daily intake of fat, carbohydrate, and protein over three main meals.

Side Effects of Generic Xenical (Orlimac Capsules)

The most common side effects reported in patients treated with Generic Xenical (Orlimac Capsules) are Gastrointestinal (GI) symptoms like Oily Spotting, Flatus with Discharge, Fecal Urgency, Fatty/Oily Stool, Oily Evacuation, Increased Defecation and Fecal Incontinence

Generic Xenical (Orlimac Capsules) - More Details

For more details please read the Prescription Information or watch the presentation below:

Wednesday 8 October 2014

Treatment of Hyperprolactinemic Disorders using Generic Dostinex

What are Hyperprolactinemic Disorders?

The medical condition which shows the presence of abnormally-high levels of prolactin in the blood is referred to as Hyperprolactinaemia or hyperprolactinemia (HP).
High levels of prolactin are associated with abnormal menstrual cycles in females and gonadal disorders in males. Hypogonadism is commonly associated with hyperprolactinemia and can cause many of the symptoms associated with raised prolactin levels. These symptoms can include oligomenorrhea (infrequent menstruation with markedly diminished menstrual flow) or amenorrhea (lack of menstrual cycles), and/or galactorrhea (excessive or spontaneous secretion of milk). Other symptoms of hyperprolactinemia in women can include decreased libido, hirsutism (condition of abnormal hairiness), acne, infertility, habitual abortion, and osteopenia. Infertility due to hyperprolactinemia is most often caused by chronic anovulation, defective folliculogenesis, and luteal phase inadequacy.
In men, the most common symptoms of hyperprolactinaemia are decreased libido, erectile dysfunction, infertility and gynaecomastia.

Generic Dostinex Tablets – Product Information

Generic Dostinex Tablets are prescribed to reduce your body’s level of a hormone known as prolactin. Generic Dostinex is used for the treatment of dysfunctions associated with hyperprolactinaemia, including amenorrhoea, oligomenorrhoea, anovulation and galactorrhoea. Cabgolin is also indicated in patients with prolactin-secreting pituitary adenomas. Generic Dostinex (Cabgolin Tablets) can also be prescribed to prevent the production of milk in women after birth, if breast-feeding is to be prevented for medical reasons. Generic Dostinex suppresses physiological lactation by inhibiting prolactin secretion.

Generic Dostinex (Cabgolin Tablets) - Active Ingredient

The active ingredient present in Generic Dostinex (Cabgolin Tablets) is Cabergoline.

Generic Dostinex (Cabgolin Tablets) - Contraindications

Generic Dostinex is contraindicated in patients that have hypersensitivity to cabergoline or any inactive component of this medicine or any ergot alkaloid. It is also contrindicated in patients with a history of pulmonary, pericardial and retroperitoneal fibrotic disorders. Anatomical evidence of cardiac valvulopathy of any valve as determined by pre-treatment echocardiogram showing valve leaflet thickening, valve restriction, valve mixed restriction-stenosis.

Generic Dostinex (Cabgolin Tablets) - Dosage

The recommended dosage of for various indications is given below:
Treatment of Hyperprolactinaemic Disorders:
To treat high levels of prolactin (hyperprolactinaemia), the recommended starting dose is 0.25mg taken twice a week.The weekly dose should be increased gradually preferably by adding 0.5mg per week at monthly intervals until the optimal therapeutic response is achieved.
Inhibition of Lactation:
To prevent the production of milk, the recommended dose is 1mg (two 0.5mg tablets) as a single dose taken once, on the first day after delivery.

Side Effects of Generic Dostinex (Cabgolin Tablets)

The most frequently occurring side effects include dizziness/vertigo, headache, pain in the stomach, nausea and abdominal pain or heartburn. Rarely occuring side effects were palpitations, epigastric pain, somnolence, epistaxis and transient hemianopsia, vomiting, syncope, asthenia, and hot flushes were reported.Most side effects were transient and mild to moderate in severity.

Generic Dostinex - More Details

For more details please read the prescription information or watch the presentation below:

Tuesday 7 October 2014

Migraine Headache Relief using Generic Imitrex

What is a Migraine Headache?

Migraine is a chronic disorder that is thought to involve abnormal functioning of the brain's blood vessels.Migraines cause severe pain on one or both sides of the head, upset stomach, nausea, and, at times, disturbed vision. Persons who have experienced migraines have described migraine pain as pulsing or throbbing in one area of the head. During migraines, people become very sensitive to light and sound.

Generic Imitrex Tablets - Product Information

Generic Imitrex (Suminat tablets manufactured by Sun Pharma) are used for the acute relief of migraine attacks with or without aura. Generic Imitrex tablets should not be used for prevention of migraine headaches.

Dosage and Administration

The recommended adult dose of oral Imitrex is a single 50mg tablet which has to be administered as early as possible after the onset of a migraine headache. Some patients may require 100 mg. A second dose should only be considered if some response to the first dose was observed. The doses should be by separated by at least 2 hours. The maximum dosage in a 24-hour period is 200 mg.
The maximum single dose in patients with mild to moderate hepatic impairment should not exceed 50 mg. It is equally effective irrespective of the stage of the migraine attack. The tablets should be swallowed whole with water. Do not crush or chew the tablet.

Generic Imitrex Tablets - Contraindications

Generic Imitrex (Suminat Tablets) are contraindicated in persons that have a hypersensitivity to Sumatriptan Succinate or any other component of the medicine. Imitrex Tablets should not be given to patients with history, symptoms, or signs of ischemic cardiac, cerebrovascular, or peripheral vascular syndromes. In addition, patients with other significant underlying cardiovascular diseases should not be administered Imitrex Tablets. Imitrex Tablets are also contraindicated in patients with severe hepatic impairment.

Side Effects of Generic Imitrex Tablets

The common side effects of Generic Imitrex (Suminat Tablets) are dyspnoea, nausea, vomiting, feeling of sleepiness, dizziness or tiredness, sensations of heaviness, feelings of weakness, fatigue, pain, tingling, heat or flushing in any part of the body, sensations of heat or cold, pressure or tightness, problems with your eyesight, feeling of faintness or "pass out", shaking or tremors and shortness of breath.
Tell your doctor immediately if you experience any of the following serious side effects after taking Generic Imitrex:
feel heaviness, pressure or tightness in any part of the body including the chest or throat
feel irregular heartbeats - too fast or too slow
have a fit or convulsion
have wheezing, swelling of the lips or mouth, difficulty in breathing, hayfever, lumpy rash ("hives") or fainting.
These side effects are likely to be serious. Stop taking Generic Imitrex (Suminat Tablets) and seek medical attention immediately.

Generic Imitrex Tablets - More Details

For more details please refer to the prescription information or watch the presentation below:

Thursday 2 October 2014

Treatment of GERD, Gastric & Duodenal Ulcer With Generic Prilosec

Generic Prilosec (Omez Capsules) – Product Information

Generic Prilosec (Omez Capsules) is a medicine which is a proton pump inhibitor. It is used in the treatment of dyspepsia, peptic ulcer disease (PUD) (Gastric and Duodenal), gastroesophageal reflux disease (GORD/GERD), laryngopharyngeal reflux (LPR) and Zollinger-Ellison syndrome. Generic Prilosec (Omez Capsules, manufactured by Dr. Reddy's Laboratories Ltd.) is available in tablets of 10 mg, 20 mg and 40 mg.

Generic Prilosec (Omez Capsules) - Indications

Generic Prilosec is used to treat the symptoms of reflux oesophagitis or reflux disease (GERD) in adults and in children. This can be caused by "washing back" (reflux) of food and acid from the stomach into the oesophagus(food pipe). Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn, which usually occurs after eating or at night and which worsens when bending over. Omeprazole is also used to treat acid-related dyspepsia and peptic ulcers. Depending on the position of the ulcer it is called a gastric or duodenal ulcer. Peptic Ulcers Associated with Helicobacter pylori Infection are treated with a combination of Generic Prilosec and antibiotics. When Generic Prilosec is taken together with two antibiotics, they are more effective than taken one or two at a time. Generic Prilosec is also used to heal and prevent ulcers associated with non-steroidal anti-inflammatory drugs (NSAIDs) which are commonly taken to relieve pain, swelling and other symptoms of inflammation, including arthritis. Generic Prilosec is also used to treat a rare condition called Zollinger-Ellison syndrome, where the stomach produces large amounts of acid, much more than in ulcers or reflux disease.

Generic Prilosec (Omez Capsules) - Contraindications

Generic Prilosec (Omez Capsules) is contraindicated in patients that have hypersensitivity to Omeprazole Magnesium or any inactive component of this medicine.

Generic Prilosec (Omez Capsules) - Dosage

Swallow Omeprazole capsules whole with a glass of water. Do not crush or chew. The recommended dosage of for various indications is given below:
Short-Term Treatment of Active Duodenal Ulcer:
The recommended dosage is 20 mg Once daily for 4 weeks. Some patients may require an additional 4 weeks Gastric Ulcer:
The recommended dosage is 40 mg Once daily for 4 to 8 weeks H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence:
Triple Therapy: consisting of a combination of Prilosec 20 mg, Amoxicillin 1000 mg and Clarithromycin 500 mg. Each medicine twice daily for 10 days
Dual Therapy: Prilosec 40 mg Once daily for 14 days and Clarithromycin 500 mg Three times daily for 14 days
GERD:
The recommended dosage is 20 mg Once daily for 4 to 8 weeks
Maintenance of Healing of Erosive Esophagitis:
The recommended dosage is 20 mg Once daily
Pathological Hypersecretory Conditions:
The recommended dosage is 60 mg Once daily (varies with individual patient)

Generic Prilosec (Omez Capsules) - Missed Dose

If you forget to take a dose, take it as soon as you remember, and then go back to taking it as you would normally. If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Do not take a double dose to make up for the dose that you missed.

Side Effects of Generic Prilosec (Omez Capsules)

The side effects of Generic Prilosec (Omez Capsules) Tablets include diarrhoea, wind (flatulence) or constipation, nausea and/or vomiting, stomach pain or discomfort,dry mouth, skin rash, itching, headache and/or dizziness, breast enlargement in men and unusual hair loss or thinning.
Inform your doctor as soon as possible in case you notice any of the following:

  • Muscle pain or weakness, joint pain
  • "Pins and needles" (tingling or numbness of the hands and feet)
  • Changes in sleep patterns
  • changes in mood
  • Hallucinations or confusion
  • Bleeding or bruising more easily than normal, nose bleeds
  • Frequent infections such as fever, severe chills, sore throat or mouth ulcers
In case you notice any of the very rare but very serious side effects below, inform your doctor immediately or go to Accident and Emergency at the nearest hospital
  • Severe skin reaction which may include redness, blistering and peeling of the skin, accompanied with fever and chills, aching muscles
  • Ulcers, blisters or bleeding of the lips, eyes, mouth, nose and genitals
  • Swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.

Generic Prilosec (Omez Capsules) - More Details

For more details please read the prescription information or watch the presentation below:


Saturday 27 September 2014

Treatment of Duodenal and Gastric Ulcers Using Generic Zantac Tablets

What are Peptic Ulcers?

If a breakdown of the protective lining of of the stomach or the first part of the small intestine (duodenum) occurs it causes inflammation, which is termed as a Peptic Ulcer. A peptic ulcer in the stomach is called a gastric ulcer, whereas an ulcer in the duodenum is called a duodenal ulcer. It is defined as mucosal erosions equal to or greater than 0.5 cm.
Symptoms of a peptic ulcer can include abdominal pain, bloating and abdominal fullness, waterbrash(rush of saliva after an episode of regurgitation to dilute the acid in esophagus), nausea, and copious vomiting, loss of appetite and weight loss, hematemesis (vomiting of blood) and melena (tarry, foul-smelling feces due to oxidized iron from hemoglobin). On rare occassions, an ulcer can lead to a gastric or duodenal perforation, which leads to acute peritonitis and is extremely painful. Immediate surgery is required to treat a Duodenal perforation

Causes of Peptic Ulcers

A major causative factor (60% of gastric and up to 90% of duodenal ulcers) of Peptic Ulcers is chronic inflammation caused by bacteria called Helicobacter pylori that colonizes the antral mucosa. The immune system is unable to clear the infection, despite the appearance of antibodies. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Generic Zantac Tablets – Product Information

Generic Zantac (Zinetac Tablets) is used in treatment of peptic ulcers (gastric and duodenal ulcers), Gastroesophageal Reflux Disease (GERD), Zollinger-Ellison syndrome and scleroderma oesophagitis and to prevent duodenal ulcers and reflux disease from recurring. The active ingredient in Generic Zantac (Zinetac Tablets) is Ranitidine Hydrochloride. Generic Zantac (Zinetac Tablets) is available in tablets of 150 mg and 300 mg. Each Generic Zantac 150 Tablet for oral administration contains 168 mg of Ranitidine HCl equivalent to 150 mg of ranitidine.

Generic Zantac (Zinetac Tablets) - Contraindications

Generic Zantac is contraindicated in patients that have hypersensitivity to Ranitidine Hydrochloride or any inactive component of this medicine.

Generic Zantac Tablets - Dosage

The recommended dosage of Generic Zantac for various indications is given below:
Active Duodenal Ulcer: The recommended adult oral dosage of Generic Zantac for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The current recommended adult oral dosage is 150 mg twice daily.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice daily.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice daily.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg or 10 mL of syrup 4 times daily.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice daily.

Side Effects of Generic Zantac (Zinetac Tablets)

The side effects of Generic Zantac Tablets include headache, tiredness, dizziness, joint or muscle pains, diarrhoea, constipation, nausea (feeling sick), vomiting, stomach cramps or pain, sleeping problems, hair loss, decreased sex drive, impotence, abnormal uncontrolled movements, muscle twitching or spasms.Inform your doctor immediately if you notice any of the following serious side effects:

  • yellowing of the skin or eyes
  • depression, confusion, hallucinations
  • fast, slow or irregular heartbeat
  • severe upper stomach pain together with nausea or vomiting
  • signs of frequent infections such as fevers, chills, sore throat or mouth ulcers
  • bruising or bleeding more easily than normal
  • general ill health associated with weight loss
  • fever
  • skin rash, redness, itching.

In case any of the following rare side effects occur, stop taking the medication tell your doctor immediately, or go to Accident and Emergency at the nearest hospital:

  • hives or severe skin reactions
  • swelling of the face, mouth, throat or limbs
  • chest tightness, shortness of breath or difficulty breathing.

Generic Generic Zantac - More Details

For more details please read the prescription information or watch the presentation below:

Thursday 25 September 2014

Treatment of Myasthenia Gravis, Paralytic Ileus & Postoperative Urinary Retention using Generic Mestinon

What is Myasthenia Gravis?

Myasthenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigability. An autoimmune disorder occurs when the body's immune system mistakenly attacks healthy tissue. In people who suffer from myasthemia gravis, the body produces antibodies that block the muscle cells from receiving messages (neurotransmitters) from the nerve cell.
The external symptoms of myasthenia gravis is fatigability. Muscles become progressively weaker during periods of activity and improve after periods of rest. Muscles that control eye and eyelid movement, facial expressions, chewing, talking, and swallowing are especially susceptible. The muscles that control breathing and neck and limb movements can also be affected. Often, the physical examination yields results within normal limits.

Generic Mestinon (Distinon Tablets) – Product Information

Generic Mestinon (Distinon Tablets, manufactured by Samarth Pharma) is used to treat muscle weakness in people with myasthenia gravis, and to combat the effects of curariform drug toxicity. It is also used to treat paralytic ileus, postoperative urinary retention and orthostatic hypotension.

Generic Mestinon (Distinon Tablets) - Contraindications

Generic Mestinon are contraindicated in patients that have a hypersensitivity to Pyridostigmine Bromide or any inactive component of this medication. They are also contraindicated in the following cases:
Generic Mestinon should not be given to patients with mechanical gastrointestinal or urinary obstruction.
Generic Mestinon should not be used in conjunction with depolarising muscle relaxants such as suxamethonium as neuromuscular blockade may be potentiated and prolonged apnoea may result.

Generic Mestinon (Distinon Tablets) - Dosage

The dosage of Generic Mestinon for various indications is given below:
Myasthenia Gravis
Adults: Doses of 30 to 120 mg by mouth are given at intervals throughout the day when maximum strength is needed (for example on rising and before meal times). The usual duration of action of a dose is three to four hours.
Other indications:
The usual dose is 1 to 4 tablets of 60 mg by mouth

Side Effects of Generic Mestinon

The common side effects of Generic Mestinon tablets are nausea and vomiting, increased salivation, diarrhoea and abdominal cramps.

Generic Mestinon (Distinon Tablets) - Warnings and Precautions

The precautions to be taken when undergoing thereapy with Generic Mestinon are:
Hypersensitivity reactions may occur in susceptible individuals.
Extreme caution is required when administering Generic Mestinon to patients with bronchial asthma.
Care should be taken in patients with bradycardia, recent coronary occlusion, hypotension, vagotonia, epilepsy or Parkinsonism.
There is no evidence to suggest that Generic Mestinon has any special effects in the elderly. However, elderly patients may be more susceptible to dysrhythmias than the younger adult.
Generic Mestinon is mainly excreted unchanged by the kidney, therefore lower doses may be required in patients with renal disease and treatment should be based on titration of drug dosage to effect.
Generic Mestinon should not be given during cyclopropane or halothane anaesthesia; however, it may be used after withdrawal of these agents.

Generic Mestinon Tablets) - More Details

For more details please read the Prescription Information or watch the presentation below:

Monday 22 September 2014

Treatment Of Genital Warts and Actinic Keratosis Using Generic Aldara Cream

Generic Aldara Cream (Imiquad 5% Cream) – Product Information

Generic Aldara Cream (Imiquad 5% Cream, manufactured by Gracewell) is an immune response modifier for topical administration. Generic Aldara Cream is used for the topical treatment of Clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses (AK) on the face or scalp in immunocompetent adults.
Biopsy-confirmed, primary superficial basal cell carcinoma (sBCC) in immunocompetent adults when surgical methods are medically less appropriate and patient follow-up can be reasonably assured.
External genital and perianal warts/condyloma acuminata in patients 12 years old or older.

Generic Aldara Cream - Active Ingredient

The active pharmaceutical ingredient present in Generic Aldara Cream is Imiquimod.
Each 0.25 gram single sachet of Imiquad Cream contains 12.5 mg of imiquimod in an off-white oil-in-water vanishing cream base.

Generic Aldara Cream (Imiquad 5% Cream) - Contraindications

Generic Aldara Cream is contraindicated in patients with the following conditions:

  • Generic Aldara Cream is contraindicated in patients with hypersensitivity to imiquimod or inactive ingredients present in the cream.

Imiquad 5% Cream - Dosage

The dosage for various indications is given below:
Actinic keratosis: 2 times per week for a full 16 weeks
Superficial basal cell carcinoma: 5 times per week for a full 6 weeks.
External genital warts (EGW): 3 times per week until total clearance or a maximum of 16 weeks
Generic Aldara cream is to be applied prior to normal sleeping hours, and left on the skin for 6-10 hours. Hand washing before and after cream application is recommended.
Imiquimod 5% cream is packaged in single use packets which contain sufficient cream to cover an area of up to 20 cm2. A thin layer of the cream is applied to the affected area and rubbed in until the cream is no longer visible.

Side Effects of Generic Aldara Cream

The most common possible side effects reported in patients treated with Generic Aldara Cream with an incidence rate 28% or more are application site reactions or local skin reactions: itching, burning, erythema, flaking/scaling/dryness, scabbing/crusting, edema, induration, excoriation, erosion, ulceration.
The other reported Side Effects of Imiquad 5% Cream with Incidence rate 1% or more include fatigue, fever, and headache.

Generic Aldara Cream - More Details

For more details please read the Prescription Information or watch the presentation below:



Thursday 18 September 2014

Treatment of Type 2 Diabetes Using Generic Janumet Tablets

Generic Janumet® (Zita-Met Tablets) – Product Information

Generic Janumet® (Zita-Met tablets, manufactured by Glenmark Pharmaceuticals) is a prescription medicine that contains two prescription diabetes medicines, Sitagliptin Phosphate (Generic Januvia®) and Metformin HCl. Generic Janumet® can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

Generic Janumet (Zita-Met Tablets) - Active Ingredients

The active ingredients present in Generic Janumet® are Sitagliptin Phosphate and Metformin HCl.

Dosage And Administration

Zita-Met comes as an oral tablet in Sitagliptin 50 mg / Metformin 500 mg dosage form.
The dosage of anti-hyperglycaemic therapy with Generic Janumet should be individualised on the basis of the patient's current regimen, effectiveness, and tolerability while not exceeding the maximum recommended daily dose of 100 mg sitagliptin.
Generic Janumet should generally be given twice daily with meals, with gradual dose escalation, to reduce the gastrointestinal (GI) adverse effects associated with metformin. The starting dose of Zita-Met (Generic Janumet) is usually Sitagliptin (50 mg) + Metformin (500mg) twice daily with meals.

Generic Janumet (Zita-Met Tablets) - Contraindications

Generic Janumet is contraindicated in persons who have shown hypersensitivity to the active ingredients Sitagliptin Phosphate, Metformin HCl or any inactive ingredients of this formulation. It is also contraindicated in individuals with Renal dysfunction, e.g., serum creatinine equal to or greater than 1.5 mg/dL [males], equal to or greater than 1.4mg/dL [females] or abnormal creatinine clearance. Generic Janumet is also contraindicated in cases of Metabolic acidosis, including diabetic ketoacidosis.

Generic Janumet (Zita-Met Tablets) - Warnings

Lactic acidosis: The patient should be warned against excessive alcohol intake. Generic Janumet is not recommended in hepatic impairment and is contraindicated in renal impairment. Ensure normal renal function before initiating and at least annually thereafter.
Radiologic Studies: Temporarily discontinue Generic Janumet in patients undergoing radiologic studies with intravascular administration of iodinated contrast materials or any surgical procedures necessitating restricted intake of food or fluids.
Acute Pancreatitis: There have been postmarketing reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis. If pancreatitis is suspected, promptly discontinue Generic Janumet (Zita-Met tablets).
Renal Failure: There have been postmarketing reports of acute renal failure, sometimes requiring dialysis. Before initiating Generic Janumet (Zita-Met tablets)and at least annually thereafter, assess renal function and verify as normal.
Vitamin B12 Deficiency: Metformin may lower Vitamin B12 levels. Measure hematologic parameters annually.
Risk Of Hypoglycemia: When used with an insulin secretagogue (e.g., sulfonylurea) or with insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.

Side Effects of Generic Janumet (Zita-Met Tablets)

The common side effects reported in 1% or more of patients receiving combination therapy of Sitagliptin Phosphate and Metformin HCl (Generic Janumet) are Diarrhoea, Headache, Nausea, Upper respiratory tract infections, Dyspepsia, Flatulence, Vomiting, Gastrointestinal adverse reactions, Hypoglycaemia on concomitant use with other anti-diabetic drugs and Allergic reactions.

More Details

For more details on Generic Janumet please read the prescription information or watch the presentation below.


Wednesday 17 September 2014

Treatment of Depression and Nerve Pain using Generic Elavil Tablets

Generic Elavil (Tryptomer Tablets) – Product Information

Generic Elavil (Tryptomer Tablets) is used to treat symptoms of depression.Endogenous depression is more likely to be alleviated than are other depressive states. Amitriptyline Hydrochloride (Generic Elavil) is different from other pain relief drugs and is used to improve your pain control for nerve pain, for example shooting, stabbing or burning pains.

Generic Elavil (Tryptomer Tablets) - Active Ingredient

The active ingredient present in Generic Elavil Tablets (Tryptomer manufactured by Wockhardt Ltd.) is Amitriptyline Hydrochloride.

Generic Elavil Tablets - Contraindications

Generic Elavil Tablets is contraindicated in persons who have shown hypersensitivity to the active ingredient Amitriptyline Hydrochloride or any inactive ingredients of this formulation. It should not be given concomitantly with monoamine oxidase inhibitors. Hyperpyretic crises, severe convulsions, and deaths have occurred in patients receiving tricyclic antidepressant and monoamine oxidase inhibiting drugs simultaneously. Generic Elavil should not be given with Cisapride due to the potential for increaded QT interval and increased risk for arrhythmia. Tryptomer Tablets is not recommended for use during the acute recovery phase following myocardial infarction.

Generic Elavil Tablets - Warnings

Generic Elavil may block the antihypertensive action of guanethidine or similarly acting compounds. Tryptomer Tablets should be used with caution in patients with a history of seizures and in patients with a history of urinary retention, angle-closure glaucoma or increased intraocular pressure. Tricyclic antidepressant drugs, including Generic Elavil, particularly when given in high doses, have been reported to produce arrhythmias, sinus tachycardia, and prolongation of the conduction time. Myocardial infarction and stroke have been reported with drugs of this class.
Close supervision is required when Generic Elavil is given to hyperthyroid patients or those receiving thyroid medication. Generic Elavil may enhance the response to alcohol and the effects of barbiturates and other CNS depressants.

Generic Elavil Tablets - Storage Instructions

Keep Generic Elavil Tablets in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Protect the medication from light and do not allow it to freeze. Throw away any medication that is outdated or no longer needed.

Generic Elavil Tablets - Dosage

The dosage of Generic Elavil Tablets for various indications is given below:
Pain Relief:
The recommended starting dose for Amitriptyline HCl for pain is 10mg once a day. The dose is usually taken 1 or 2 hours before normal sleep time. Take the dose regularly every day. It may be 2 weeks before you start to see a real benefit. Your dose of Generic Elavil (Tryptomer Tablets) may be slowly increased to between 50mg and 75mg a day depending on how helpful it is for your pain relief.

Treatment of Depression:
The recommended initial dosage for adults is 75 mg of Amitriptyline HCl (Tryptomer Tablets) a day in divided doses. If necessary, this may be increased to a total of 150 mg per day. Increases are made preferably in the late afternoon and/or bedtime doses.

Generic Elavil Tablets - Side effects

The common side effects of Generic Elavil Tablets are given below:
Cardiovascular:
Cardiovascular Hypotension, syncope, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke, non-specific ECG changes and changes in AV conduction. CNS and Neuromuscular:
Confusional states; disturbed concentration; disorientation; delusions; hallucinations; excitement; anxiety; restlessness; drowsiness; insomnia; nightmares; numbness; tingling, and paresthesias of the extremities; peripheral neuropathy; incoordination; ataxia; tremors; coma; seizures; alteration in EEG patterns; extrapyramidal symptoms, including abnormal involuntary movements and tardive dyskinesia; dysarthria; tinnitus.
Anticholinergic:
Dry mouth, blurred vision, mydriasis, disturbance of accommodation, increased intraocular pressure, constipation, paralytic ileus, hyperpyrexia, urinary retention, dilatation of urinary tract.
Allergic:
Skin rash, urticaria, photosensitization, oedema of face and tongue.
Haematologic:
Bone marrow depression including agranulocytosis, leukopenia, eosinophilia, purpura, thrombocytopenia.
Gastrointestinal:
Nausea, epigastric distress, vomiting, anorexia, stomatitis, peculiar taste, diarrhoea, parotid swelling, black tongue, rarely hepatitis (including altered liver function and jaundice).
Endocrine:
Testicular swelling and gynecomastia in the male, breast enlargement and galactorrhea in the female, increased or decreased libido, impotence, elevation or lowering of blood sugar levels, syndrome of inappropriate ADH (antidiuretic hormone) secretion.
Other:
Dizziness, weakness, fatigue, headache, weight gain or loss, oedema, increased perspiration, urinary frequency, mydriasis, drowsiness, alopecia.

Generic Elavil Tablets - More Details

For more details please watch the presentation below:



Tuesday 16 September 2014

Lighten Darkened Areas of Skin using Generic Aclaro Cream

Causes of Skin Discoloration

Skin discoloration results from certain abnormalities in the body metabolism which can have opne or more reasons. The main reasons are Diseases, Medications, Pregnancy and Diet. In addition to these factors, change in skin color is also brought about by extreme climatic conditions, aging, and heredity.

Generic Aclaro Cream (Melalite Cream) – Product Information

Generic Aclaro Cream (Melalite Cream, manufactured by Abbott) is used for the treatment of ultraviolet induced dyschromia and discoloration resulting from the use of oral contraceptives, pregnancy, hormone replacement therapy, or skin trauma. The active ingredient present in Generic Aclaro Cream is Hydroquinone 4%.

Generic Aclaro Cream - Active Ingredient

The active pharmaceutical ingredient contained in Generic Aclaro Cream is Hydroquinone.

Generic Aclaro Cream (Melalite Cream) - Contraindications

Generic Aclaro Cream is contraindicated in any patient that has a hypersensitivity or allergic reaction to hydroquinone or any of the other ingredients present in Generic Aclaro.

How Does it Work

Topical application of Hydroquinone (Generic Aclaro Cream) produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation and suppression of other melanocyte metabolic processes.

Generic Aclaro Cream - Dosage

Melalite Cream (Generic Aclaro) should be applied to the affected areas twice daily, or as directed by your doctor.

Side Effects of Generic Aclaro Cream (Melalite Cream)

No systemic reactions have been reported in users of Melalite Cream. Occasional cutaneous hypersensitivity (localized contact dermatitis) may occur, in which case the medicine should be stopped and the doctor informed immediately.

Generic Aclaro Cream (Melalite Cream) - More Details

For more details please read the Prescribing Information or watch the presentation below:



Monday 15 September 2014

Treatment of Rhinitis Using Generic Flonase Nasal Spray

What is Rhinitis?

Rhinitis is a medical condition which is characterised by irritation and inflammation of the mucous membrane inside the nose. This can be caused by viruses, bacteria, irritants or allergens.
The inflammation results in the generation of large amounts of mucus, which results in a stuffy nose, runny nose, and post-nasal drip. In the case of allergic rhinitis, the inflammation is caused by the degranulation of mast cells in the nose. Allergic rhinitis is usually triggered by airborne allergens such as pollen molds, dust mites, animal hair, industrial chemicals foods, medicines, and insect venom.
The other types of Rhinitis are Seasonal allergic rhinitis or hayfever (occurs in late summer or spring), Perennial allergic rhinitis (occurs year-round) and Non-Allergic Rhinitis

Generic Flonase Nasal Spray (Flomist Nasal Spray) – Product Information

Generic Flonase Nasal Spray (Flomist Nasal Spray, manufactured by Cipla) is used for the treatment of the nasal symptoms of seasonal and perennial allergic and nonallergic rhinitis in adults and pediatric patients 4 years of age and older.
The active ingredient present in Generic Flonase Nasal Spray is Fluticasone Propionate

Generic Flonase Nasal Spray (Flomist Nasal Spray) - Contraindications

Generic Flonase Nasal Spray is contraindicated in patients with a known hypersensitivity to Fluticasone Propionate or to any component of this medication

Generic Flonase Nasal Spray (Flomist Nasal Spray) - Dosage

The recommended starting dosage of Generic Flonase Nasal Spray (Flomist Nasal Spray) for adult patients is 200-mcg once-daily regimen (two 50-mcg sprays in each nostril once daily). An alternative 200-mcg/day dosage regimen can be given as 100 mcg twice daily (one 50-mcg spray in each nostril twice daily).
Some patients (12 years of age and older) with seasonal allergic rhinitis may find as-needed use of Generic Flonase Nasal Spray (not to exceed 200 mcg daily) effective for symptom control. Greater symptom control may be achieved with scheduled regular use.

Side Effects of Generic Flonase Nasal Spray

The most common side effects reported in patients treated with Generic Flonase Nasal Spray (Flomist Nasal Spray) were Headache,Pharyngitis, Epistaxis, Nasal burning/nasal irritation, Nausea/vomiting, Asthma symptoms, and Cough. Intranasal corticosteroids may cause a reduction in growth velocity when administered to pediatric patients . Other side effects that occurred in 1% or more but less than 3% of patients and that were more common with fluticasone propionate included: blood in nasal mucus, runny nose, abdominal pain, diarrhea, fever, flu-like symptoms, aches and pains, dizziness, bronchitis.

Generic Flonase Nasal Spray - More Details

For more details please read the Prescription Information or watch the presentation below:



Friday 12 September 2014

Treatment and Prevention of Nausea & Vomiting using Gravol Tablets

Gravol Tablets – Product Information

Gravol is a brand name for the over the counter drug dimenhydrinate. Gravol Tablets are available in strengths of 50 mg. Gravol is also known as Dramamine, Driminate, Gravamin, Vomex, Vertirosan, Viabom, Dramin, Daedalon, Antimo, Hydrate, Dramoject, Dymenate, DMH, Triptone.

Uses Of Gravol Tablets

Gravol Tablets manufactured by Wallace Pharmaceuticals, India are indicated for the treatment or prevention and treatment of various forms of motion sickness, vomiting and dizziness due to motion sickness, prevention and treatment of nausea, Ménière's syndrome, vertigo due to other labyrinthine disorders, postoperative vomiting, medicine induced nausea and vomiting associated with radiation therapy, and migraine.

Dosage And Administration

The recommended adult dose is 50-100 mg with dosage repeated every 4 hours as required. Maximum daily oral dose is 500 mg. Avoid alcoholic beverages or any product containing alcohol while taking Dimenhydrinate. The recommended Children's Dosage is given below:
6-8 years: 15-25 mg, two or three times daily
8-12 years: 25-50 mg, two or three times daily
Over 12 years: 50 mg, two or three times daily

Gravol Tablets Side Effects

Gravol Tablets (Dimenhydrinate) can cause drowsiness, excitement or hyperactivity (especially in children), headache, ringing in the ears, dry mouth, nose, or throat, problems with coordination, fainting, nausea, dizziness and blurred vision. It can also impair your concentration and motor coordination. Hence you should not drive or do other things that require you to be fully alert. It can be especially dangerous to combine it with alcohol and other depressant drugs. The other side effects are dry mouth, excitation and nervousness. In case you experience the rarely occuring but serious side effects such as fast, pounding, or irregular heartbeat call your doctor immediately.

More Details

For more details please see the presentation below.

Thursday 11 September 2014

Contraception and Treatment of Severe Acne and Idiopathic Hirsutism with Diane-35

What is Hirsutism?

Hirsutism in women causes a male pattern of body hair, sometimes excessive, particularly in locations where women normally do not develop terminal hair during puberty (chest, abdomen, back and face). Hirsutism can be caused by either an increased level of androgens, the male hormones, or an oversensitivity of hair follicles to androgens. Another common cause of hirsutism is polycystic ovarian syndrome (PCOS).
The top symptom of hirsutism is hair growth on the abdomen, breasts, and upper lip (male-pattern hair growth in women). If hirsutism is caused by high levels of male hormones, symptoms can also include Irregular menstrual periods, Acne, Loss of feminine body shape and Signs of masculinity such as deepening voice, male pattern baldness, enlarged clitoris and enlarged shoulder muscles.
A common pharmacological treatment is Cyproterone acetate, a progestin that also has strong antiandrogenic action. In addition to single form, it is also available in some formulations of combined oral contraceptives like Diane-35 .

Diane-35 Tablets – Product Information

Diane-35 tablets manufactured by Bayer Schering Pharma is used as a oral contraceptive as well for the the treatment of signs of androgenisation in women, such as severe acne (involving inflammation or nodularity or risk of scarring) where prolonged oral antibiotics or local treatment alone has not been successful, or idiopathic hirsutism (excess hair on the face, chest, abdomen or legs), of mild to moderate degree.
The most important factors that cause the contraceptive effect of Diane-35 are the inhibition of ovulation and the changes in the cervical secretion.
Treatment with Diane-35 for 3 to 4 months leads to the healing of existing acne efflorescences. The excessive greasiness of the hair and skin generally disappears earlier. The loss of hair which frequently accompanies seborrhoea likewise diminishes. In women experiencing mild forms of hirsutism and in particular, slightly increased facial hair, results do not, however become apparent until after several months of use.

Diane-35 Tablets - Contraindications

Diane-35 is contraindicated in patients with

  • Hypersensitivity to the active ingredients cyproterone acetate and/or ethinyl estradiol or to any of the other components of the medicine.
  • Personal or family history of confirmed, idiopathic venous thromboembolism (VTE)(where a family history refers to VTE in a sibling or parent at a relatively early age).
  • Presence or a history of venous or arterial thrombotic/thromboembolic events (e.g. deep venous thrombosis, pulmonary embolism, myocardial infarction) or of a cerebrovascular accident.
  • Sickle-cell anaemia
  • Presence or history of prodromi of a thrombosis (e.g. transient ischaemic attack, angina pectoris).
  • Presence of severe or multiple risk factor(s) for venous or arterial thrombosis
  • History of migraine with focal neurological symptoms.
  • Diabetes mellitus with vascular involvement.
  • Pancreatitis or a history thereof if associated with severe hypertriglyceridemia.Severe hepatic disease as long as liver function values have not returned to normal.Jaundice or persistent itching during a previous pregnancy, Dubin-Johnson syndrome, Rotor syndrome
  • History of deterioration of otosclerosis during pregnanacy.
  • Presence or history of liver tumors (benign or malignant).
  • Known or suspected sex steroid influenced malignancies (e.g. of the genital organs or the breasts).
  • Undiagnosed vaginal bleeding.
  • Known or suspected pregnancy.
  • Lactation.
  • Disorders of lipid metabolism
  • History of herpes gestationis

Diane-35 Tablets - Dosage

The recommended adult Oral dosage of Diane-35 Tablets is one tablet is to be taken daily. The tablets must be taken at about the same time every day, with some liquid as needed. Tablet taking should be continuous. One tablet of Diane-35 is to be taken daily for 21 consecutive days. Withdrawal bleeding should usually occur on day 2 to 3 after the last tablet is taken. Each subsequent pack is started after a 7 day tablet free interval.
How to start Diane-35 Tablets:
Tablet taking has to start on day 1 of the woman's natural cycle (i.e. the first day of her menstrual bleeding). Starting on day 2 -5 of the menstrual cycle is permitted, but during the first cycle a barrier method is recommended in addition for the first 7 days of tablet-taking. When you have taken all 21 tablets in this pack, wait 7 days and then start a new pack of Diane-35. During the 7 days that you are not taking any tablets, you should have your period, usually 2-4 days after you have taken your last tablet.
The first tablet in every subsequent pack will always be taken on the same day of the week that you first began taking Diane-35 tablets regardless of whether your bleeding has already ceased (which it usually has) or is still continuing.

Diane-35 Tablets - Missed Dose Instructions

The management of missed tablets can be guided by the following two basic rules: Tablet-taking must never be discontinued for more than 7 days; and 7 days of uninterrupted tablet-taking are required to attain adequate suppression of the hypothalamic-pituitary-ovarian axis.
If the user is less than 12 hours late in taking a tablet, contraceptive protection is not reduced. The woman should take the tablet as soon as she remembers and should take further tablets at the usual time.
Week 1: The user should take the last missed tablet as soon as she remembers, even if this means taking 2 tabs at the same time. She then continues to take tablets at her usual time. In addition, a barrier method eg, a condom, should be used for the next 7 days.
Week 2: The user should take the last missed tablet as soon as she remembers, even if this means taking 2 tabs at the same time. She then continues to take tablets at her usual time. Provided that the woman has taken her tablets correctly in the 7 days preceding the 1st missed tablet, there is no need to use extra contraceptive precautions. However, if this is not the case or if she missed more than one tablet, the woman should be advised to use extra precautions for 7 days.
Week 3: The risk of reduced reliability is imminent because of the forthcoming tablet-free interval. However, by adjusting the tablet-intake schedule, reduced contraceptive protection can still be prevented. By adhering to either of the following 2 options, there is therefore no need to use extra contraceptive precautions, provided that in the 7 days preceding the first missed tablet, the woman has taken all tablets correctly. If this is not the case, the woman should be advised to follow the first of these 2 options and to use extra precautions for the next 7 days as well.
The user should take the last missed tablet as soon as she remembers, even if this means taking 2 tablets at the same time. She then continues to take tablets at her usual time. The next pack must be started as soon as the current pack is finished i.e., no gap should be left between packs. The user is unlikely to have a withdrawal bleed until the end of the second pack, but she may experience spotting or breakthrough bleeding on tablet-taking days.

Side Effects of Diane-35 Tablets

The most common side effects (1% or more) reported in patients treated with Diane-35 Tablets are nausea, abdominal pain, weight increased, headache,depressed mood, mood altered, breast pain, breast tenderness. The uncommon side effects (Occuring in 1 per thousand or more and less than 1 in 100) are vomiting, diarrhea, fluid retention, migrane, libido decreased, breast hypertrophy, Rash, and urticaria. The rare side effects include contact lens intolerance, hypersensitivity, weight decreased, libido increased, vaginal discharge, breast discharge, Erythema nodosum and erythema multiforme.

Diane-35 - More Details

For more details please watch the presentation below: