Saturday 27 September 2014

Treatment of Duodenal and Gastric Ulcers Using Generic Zantac Tablets

What are Peptic Ulcers?

If a breakdown of the protective lining of of the stomach or the first part of the small intestine (duodenum) occurs it causes inflammation, which is termed as a Peptic Ulcer. A peptic ulcer in the stomach is called a gastric ulcer, whereas an ulcer in the duodenum is called a duodenal ulcer. It is defined as mucosal erosions equal to or greater than 0.5 cm.
Symptoms of a peptic ulcer can include abdominal pain, bloating and abdominal fullness, waterbrash(rush of saliva after an episode of regurgitation to dilute the acid in esophagus), nausea, and copious vomiting, loss of appetite and weight loss, hematemesis (vomiting of blood) and melena (tarry, foul-smelling feces due to oxidized iron from hemoglobin). On rare occassions, an ulcer can lead to a gastric or duodenal perforation, which leads to acute peritonitis and is extremely painful. Immediate surgery is required to treat a Duodenal perforation

Causes of Peptic Ulcers

A major causative factor (60% of gastric and up to 90% of duodenal ulcers) of Peptic Ulcers is chronic inflammation caused by bacteria called Helicobacter pylori that colonizes the antral mucosa. The immune system is unable to clear the infection, despite the appearance of antibodies. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Generic Zantac Tablets – Product Information

Generic Zantac (Zinetac Tablets) is used in treatment of peptic ulcers (gastric and duodenal ulcers), Gastroesophageal Reflux Disease (GERD), Zollinger-Ellison syndrome and scleroderma oesophagitis and to prevent duodenal ulcers and reflux disease from recurring. The active ingredient in Generic Zantac (Zinetac Tablets) is Ranitidine Hydrochloride. Generic Zantac (Zinetac Tablets) is available in tablets of 150 mg and 300 mg. Each Generic Zantac 150 Tablet for oral administration contains 168 mg of Ranitidine HCl equivalent to 150 mg of ranitidine.

Generic Zantac (Zinetac Tablets) - Contraindications

Generic Zantac is contraindicated in patients that have hypersensitivity to Ranitidine Hydrochloride or any inactive component of this medicine.

Generic Zantac Tablets - Dosage

The recommended dosage of Generic Zantac for various indications is given below:
Active Duodenal Ulcer: The recommended adult oral dosage of Generic Zantac for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The current recommended adult oral dosage is 150 mg twice daily.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice daily.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice daily.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg or 10 mL of syrup 4 times daily.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice daily.

Side Effects of Generic Zantac (Zinetac Tablets)

The side effects of Generic Zantac Tablets include headache, tiredness, dizziness, joint or muscle pains, diarrhoea, constipation, nausea (feeling sick), vomiting, stomach cramps or pain, sleeping problems, hair loss, decreased sex drive, impotence, abnormal uncontrolled movements, muscle twitching or spasms.Inform your doctor immediately if you notice any of the following serious side effects:

  • yellowing of the skin or eyes
  • depression, confusion, hallucinations
  • fast, slow or irregular heartbeat
  • severe upper stomach pain together with nausea or vomiting
  • signs of frequent infections such as fevers, chills, sore throat or mouth ulcers
  • bruising or bleeding more easily than normal
  • general ill health associated with weight loss
  • fever
  • skin rash, redness, itching.

In case any of the following rare side effects occur, stop taking the medication tell your doctor immediately, or go to Accident and Emergency at the nearest hospital:

  • hives or severe skin reactions
  • swelling of the face, mouth, throat or limbs
  • chest tightness, shortness of breath or difficulty breathing.

Generic Generic Zantac - More Details

For more details please read the prescription information or watch the presentation below:

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