Tuesday 2 September 2014

Treatment of Menopausal Symptoms using Generic Ovestin Tablets

Why is Hormone Replacement Therapy (HRT) Necessary?

Generic Ovestin (Evalon Pills manufactured by Organon) contains the natural female hormone oestriol. During and after menopause the oestrogen production by your body decreases which may lead to hot flushes, vaginal irritation, recurrent urinary tract infections and urinary incontinence. Evalon Tablets can be prescribed as Hormone Replacement Therapy (HRT) to treat menopausal symptoms due to the loss of oestrogen production by your body.

Generic Ovestin (Evalon Tablets) – Product Information

Generic Ovestin Tablets are used to treat atrophy of the lower urogenital tract related to oestrogen deficiency, notably for the treatment of vaginal complaints such as dyspareunia, dryness and itching, for the prevention of recurrent infections of the vagina and lower urinary tract, in the management of micturition complaints (such as frequency and dysuria) and mild urinary incontinence. It is also used for Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery, Climacteric complaints such as hot flushes and night sweating, as a diagnostic aid in case of a doubtful atrophic cervical smear and to treat infertility due to cervical hostility. Estriol (also oestriol or E3) is one of the three main estrogens produced by the human body.

Generic Ovestin (Evalon Tablets) - Active Ingredient

The active pharmaceutical ingredient contained in Generic Ovestin Tablets is Estriol (also called Oestriol or E3).

Generic Ovestin - Contraindications

Generic Ovestin Tablets is contraindicated in patients that have hypersensitivity to Estriol or any inactive component of this medication.

Generic Ovestin (Evalon Tablets) - Dosage

Atrophy of the lower urogenital tract:
4mg to 8mg per day for the first weeks, followed by a gradual reduction, based on response to the treatment, until a maintenance dosage (e.g. 1mg to 2mg per day) is reached.
Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery:
4mg to 8mg per day in the 2 weeks before surgery; 1mg to 2mg per day in the 2 weeks after surgery.
Climacteric complaints such as hot flushes and night sweating:
The recommended dosage is 4mg to 8mg per day during the first weeks, followed by a gradual reduction. The lowest effective dosage should be used. In case of long-term treatment in women with an intact uterus, monitoring of the endometrium or, alternatively, concomitant use of a progestagen is recommended.
A diagnostic aid in case of a doubtful atrophic cervical smear:
2mg to 4mg per day for 7 days before taking the next smear.
Infertility due to Cervical Hostility:
The recommended dosage is in general 1mg to 2mg per day on days 6 to 15 of the menstrual cycle. However, for some patients dosages as low as 1mg per day are sufficient, whereas others may need up to 8mg per day. Therefore, the dosage should be increased each month until an optimal effect on the cervical mucus is obtained.

Side Effects of Generic Ovestin (Evalon Tablets)

The side effects of Generic Ovestin are dependent on dosage and sensitivity of the patient. Generic Ovestin (Evalon Tablets) may cause side effects, such as:
* swelling and increased tenderness of the breasts
* vaginal bleeding
* increased vaginal discharge
* nausea
* fluid retention in the tissues, usually marked by swollen ankles or feet.
In most patients these side effects will disappear after the first weeks of treatment.

Generic Ovestin (Evalon Tablets) - More Details

For more details please watch the presentation below:

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