Monday 20 October 2014

Treatment of Chickenpox, Shingles and Genital Herpes using Generic Zovirax Tablets

What is Chickenpox?

Chickenpox (varicella) is a common illness caused by the varicella-zoster virus. Most cases are in children under age 15, causes an itchy rash and red spots or blisters (pox) all over the body. It is most common in children, but most people will get chickenpox at some point in their lives if they have not had the chickenpox vaccine. It spreads very easily from one person to another through coughing or sneezing of sick individuals or through direct contact with secretions from the rash. A person with chickenpox is infectious one to two days before the rash appears.
After you have had chickenpox, you are not likely to get it again. But the virus stays in your body long after you get over the illness. If the virus becomes active again, it can cause a painful viral infection called a style="text-decoration:underline;color:#FF3300;" href="http://en.wikipedia.org/wiki/Herpes_zoster">shingles.

Generic Zovirax – Product Information

Generic Zovirax is used for the treatment of chickenpox (varicella) and for the acute treatment of herpes zoster (shingles). It is also used for the for the treatment of initial episodes and the management of recurrent episodes of Genital Herpes.
The active ingredient present in Generic Zovirax is Aciclovir (or Acyclovir). Aciclovir is marketed under trade names such as Cyclovir, Herpex, Acivir, Acivirax, Zovirax, Zoral, and Xovir. It is one of the most commonly used antiviral drugs, it is primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of varicella zoster (chickenpox) and herpes zoster (shingles). Zovirax tablets are manufactured by GlaxoSmithKline (GSK) India and Generic Zovirax (Acivir Tablets) are manufactured by Cipla Ltd., India.

Generic Zovirax - Contraindications

Generic Zovirax is contraindicated in patients that have a hypersensitivity to Acyclovir or Valacyclovir or any inactive ingredient present in the product.

Generic Zovirax Tablets - Dosage

Zovirax (Aciclovir) comes as an oral tablet in 125 mg, 200 mg, 400 mg, and 800 mg dosage forms. Among other side effects, Generic Zovirax Tablets (Aciclovir) may cause an upset stomach. The recommended adult Oral dosage of Generic Zovirax for adults is given below:
Dosage for Treatment of Herpes Simplex (Cold Sores) in Adults
For treatment of Herpes Simplex infections (Cold Sores or Fever Blisters), 200 mg Generic Zovirax should be taken five times daily at approximately four-hourly intervals, omitting the night-time dose. Treatment should continue for 5 days but in severe initial infections may have to be extended. In severely immune-compromised patients (e.g. after marrow transplants) or in patients with impaired absorption from the gut, the dose can be doubled to 400 mg or alternatively intravenous dosing could be considered. Dosing should begin as early as possible after the start of an infection. For recurrent episodes this should preferably be during the prodromal period or when lesions first appear.

Dosage for Suppression of Herpes Simplex in Adults
For suppression of Herpes Simplex infections in immune-competent patients, 200mg Generic Zovirax should be taken four times daily at approximately six-hourly intervals. Many patients may be conveniently managed on a regimen of 400 mg Generic Zovirax taken twice daily at approximately twelve-hourly intervals. Dosage titration down to 200 mg Generic Zovirax taken thrice daily at approximately eight-hourly intervals or even twice daily at approximately twelve-hourly intervals, may prove effective. Some patients may experience breakthrough infections on total daily doses of 800 mg Generic Zovirax. Therapy should be interrupted periodically at intervals of six to twelve months in order to observe possible changes in the natural history of the disease.

Dosage for Prophylaxis of Herpes Simplex in Adults
For prophylaxis of Herpes Simplex infections in immune-compromised patients, 200 mg Generic Zovirax should be taken four times daily at approximately six-hourly intervals.

Dosage for Treatment of Herpes Zoster (Shingles) in Adults
For treatment of Herpes Zosterinfections (Shingles), 800 mg Generic Zovirax should be taken five times daily at approximately four-hourly intervals, omitting the night-time dose. Treatment should continue for seven days.

Dosage for Treatment of Genital Herpes in Adults:
Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. Alternative regimens have included doses ranging from 200 mg 3 times daily to 200 mg 5 times daily.

Treatment of Chickenpox:
Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for five days. Children over 40 kg should receive the adult dose for chickenpox. Adults and Children over 40 kg: 800 mg 4 times daily for five days.

Side Effects of Generic Zovirax

The most common side effects reported in patients treated with Generic Zovirax include Headache, dizziness, Nausea, vomiting, diarrhoea, abdominal pains, Pruritus, rashes(including photosensitivity), Fatigue, fever.
The uncommon side effects include Urticaria, accelerated diffuse hair loss. Anaphylaxis, Dyspnoea, Reversible rises in bilirubin and liver related enzymes, Angioedema and Increases in blood urea and creatinine are among the rare side effects.
The extremely rare side effects include Acute renal failure, renal pain, Hepatitis, jaundice, Agitation, confusion, tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, convulsions, somnolence, encephalopathy, coma Anaemia, leukopenia and thrombocytopenia.

Generic Zovirax Tablets - More Details

For more details on Generic Zovirax tablets please watch the presentation below:

Saturday 18 October 2014

Blood clot prevention using Generic Plavix Tablets

Generic Plavix Tablets - Product Information

Generic Plavix (Clopidogrel Bisulfate) is a platelet inhibitor and prevent blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It used to treat patients with Acute coronary syndrome (unstable angina (UA)/non-ST-segment elevation ACS (NSTEMI)& ST-elevation myocardial infarction (STEMI) ), recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease. The active ingredient present in Generic Plavix (Clopivas Tablets) is Clopidogrel Bisulfate

Generic Forms and Brand names of Clopidogrel (Generic Plavix)

Generic Plavix is available as Clopivas manufactured by Cipla Ltd., India. Generic Plavix which has the active ingredient Clopidogrel Bisulfate is also sold as Plagril as well as other brand names.

Mechanism of Action

Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets.

Generic Plavix - Contraindications

Generic Plavix (Clopivas Tablets) is contraindicated in patients with a hypersensitivity to Clopidogrel Bisulfate or any inactive component of this medication.
It is also contraindicated in patients with active pathological bleeding, such as peptic ulcer or intracranial hemorrhage.

Generic Plavix - Side Effects

Bleeding, including life-threatening and fatal bleeding, is the most commonly reported side effect of Generic Plavix (Clopivas Tablets).
Thrombotic thrombocytopenic purpura (TTP), sometimes fatal, has been reported following use of Generic Plavix, sometimes after a short duration.

Pregnancy and Nursing

Generic Plavix should be used during pregnancy only if clearly needed. Nursing mothers have to either discontinue Clopivas (Generic Plavix) or nursing, taking into consideration importance of drug to mother.

Overdosage

Platelet inhibition by Generic Plavix is irreversible and will last for the life of the platelet. Overdose following clopidogrel administration may result in bleeding complications. Platelet transfusion may restore clotting ability.

Friday 17 October 2014

Treatment of Moderate to Severe Acne Using Generic Accutane Capsules

What is Acne?

Acne vulgaris (cystic acne or simply acne) is a human skin condition characterized by areas of skin with intense erythema, inflammation, seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules), cysts, and possibly scarring.
Acne affects mostly skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Severe acne is inflammatory, but acne can also manifest in noninflammatory forms. The lesions are caused by changes in pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland, changes that require androgen stimulation.
Some of the large nodules were previously called "cysts" and the term nodulocystic has been used to describe severe cases of inflammatory acne. Oral antibacterials, were initially used as the first line therapy for severe nodular acne. However due to concerns of antibacterial adverse effects, patient adherence, and antimicrobial resistance the search for alternate therapies started and finally Isotretinoin, an oral retinoid was introduced in 1982.
Oral antibacterials are still used as an alternative for patients with severe acne who have a hypersensitivity towards oral retinoids, or for whom the use of retinoids is contraindicated.

Generic Accutane (Isotretinoin) – Product Information

Generic Accutane Capsules (Isotroin), an extremely powerful and potent acne-controlling medicine, is used to treat severe recalcitrant nodular acne that has failed other therapy. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. "Severe," by definition, means "many" as opposed to "few or several" nodules.
A single course of therapy for 15 to 20 weeks has been shown to result in complete and prolonged remission of disease in many patients. If a second course of therapy is needed, it should not be initiated until at least 8 weeks after completion of the first course.
Isotretinoin is available as Roaccutane, Isotroin, Tretiva, Amnesteem, Claravis, and Sotret. Earlier it was available as Accutane in the US market.

Generic Accutane (Isotretinoin Capsules) - Contraindications

Generic Accutane Capsules are contraindicated in patients that have a hypersensitivity to Isotretinoin or any inactive component of this medication. They are also contraindicated in the following cases:
Generic Accutane should not be given to female patients that are pregnant.

Generic Accutane (Isotroin Capsules) - Dosage

The recommended adult Oral dosage of Generic Accutane (Isotroin Capsules) is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks.
Accutane should always be administered with a meal. Failure to take Accutane with food will significantly decrease absorption.

Side Effects of Generic Accutane (Isotroin Capsules)

The side effects reported in patients treated with Generic Accutane capsules are Anemia, Increased red blood cell sedimentation rate, Thrombocytopenia, Thrombocytosis, Neutropenia, Headache, Blepharitis, Conjunctivitis, Dry eyes, Eye irritation, Epistaxis, Nasal dryness, Nasopharyngitis, Increased transaminase, Cheilitis, Dermatitis, Dry skin, Localised exfoliation, Pruritus, Rash, Erythematous, Skin fragility, Arthralgia, Myalgia, Back pain, Increased triglycerides, Decreased HDL, Increased blood cholesterol, Increased blood glucose, Haematuria, and Proteinuria.

Generic Accutane Capsules - More Details

For more details please read the Prescription Information or watch the presentation below:

Thursday 16 October 2014

Treatment of Hypertension and Angina Pectoris with Generic Norvasc Tablets

What is Hypertension?

Hypertension (HTN) or high blood pressure, sometimes called arterial hypertension, is a chronic medical condition which is characterised by elevated blood pressure in the arteries. As a result of this, the heart to work harder than normal to circulate blood through the blood vessels.
Blood pressure, which is a measurement of the force against the walls of your arteries as your heart pumps blood through your body, is summarised by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole). Normal blood pressure at rest is within the range of 100-140mmHg systolic (top reading) and 60-90mmHg diastolic (bottom reading).
High blood pressure is said to be present if it is persistently at or above 140/90 mmHg. Hypertension is a major risk factor for stroke, myocardial infarction (heart attacks), heart failure, aneurysms of the arteries (e.g. aortic aneurysm), peripheral arterial disease and is a cause of chronic kidney disease.

What is Angina Pectoris ?

Angina, or Angina Pectoris is a pain or discomfort that keeps coming back when part of your heart does not get enough blood and thus a lack of oxygen supply and waste removal. Angina feels like a pressing or squeezing pain, usually in your chest under the breastbone. Sometimes you can feel it in your shoulders, arms, neck, jaws, or back. Generic Norvasc can relieve this pain.
Angina pectoris, commonly known as angina, is chest pain due to ischemia (a lack of blood, thus a lack of oxygen supply and waste removal) of the heart muscle, generally due to obstruction or spasm of the coronary arteries (the heart's blood vessels). Coronary artery disease, the main cause of angina, is due to hardening of the coronary arteries (atherosclerosis). Treatments for angina include lifestyle changes, medicines, medical procedures, cardiac rehabilitation (rehab), and other therapies.

Generic Norvasc (Amlopres Tablets) – Product Information

Generic Norvasc (Amlopres Tablets) is a type of medication known as a calcium channel blocker (CCB). It is used to treat high blood pressure (hypertension) and a type of chest pain called angina pectoris. It can be used by itself or with other medicines to treat these conditions.

Generic Norvasc - Active Ingredient

The active ingredient present in Generic Norvasc is Amlodipine Besylate (Besilate)

Generic Norvasc - Contraindications

Generic Norvasc (Amlopres Tablets) is contraindicated in patients that have hypersensitivity to amlodipine, dihydropyridines or any inactive component of this medicine.

Generic Norvasc (Amlopres Tablets) - Dosage

Swallow Amlopres tablet whole with a full glass of water. Take your medicine at about the same time each day, either morning or evening. Taking it at the same time each day will have the best effect. Generic Norvasc can be taken with or without food.
For both hypertension and angina, the recommended initial dose is 5 mg Generic Norvasc once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily.

Side Effects of Generic Norvasc

Most side effects are mild or moderate. Tell your doctor or pharmacist if you experience any of the following common side effects of Norvasc and they worry you. The most frequently occurring side effects of Generic Norvasc (Amlopres Tablets) include swelling of the ankles, feet, face or hands, headache, dizziness, flushing, fast or irregular heart beats, tiredness, drowsiness or sleepiness, stomach pain or nausea.
Tell your doctor immediately if you notice any of the following: changes in heart beat either fast or slow chest pain chest pain associated with exertion (angina) that lasts longer, is more severe or occurs more often dizziness or lightheadedness on standing up from a sitting or lying position, eye pain or change in vision changes in mood, feeling anxious or nervous symptoms of liver disease such as itching, yellowing of the skin and eyes, and dark coloured urine.These may be serious side effects that may need urgent medical attention. Serious side effects are rare.
Inform your doctor immediately or go to Accident and Emergency at your nearest hospital, if you notice any of the following serious side effects of Generic Norvasc Tablets: shortness of breath, symptoms of allergy such as skin rash and/or itching severe upper stomach pain, often with nausea and vomiting.

Generic Generic Norvasc Tablets - More Details

For more details please read the Prescribing Information or watch the presentation below:

Wednesday 15 October 2014

Treatment of Schizophrenia, Bipolar I disorder and Major depressive disorder using Generic Abilify Tablets

Generic Abilify Tablets – Product Information

Generic Abilify which is used to treat schizophrenia, Bipolar I disorder and major depressive disorder is available as Asprito Tablets.
Asprito Tablets (Aripiprazole Tablets) manufactured by Intas Pharmaceuticals Ltd., India is approved by the Indian FDA. In addition , the active ingredient Aripiprazole is approved by the US FDA.

Generic Abilify Tablets - Contraindications

Generic Abilify tablets is contraindicated for patients with a hypersensitivity to aripiprazole or any other ingredient present in Generic Abilify tablets . Hypersensitive reactions have ranged from pruritus/urticaria to anaphylaxis.

Generic Abilify Tablets - Dosage

The recommended adult Oral dosage of Generic for adults is given below:
The recommended dosage for the treatment of Schizophrenia in adults is 10-15 mg/day with an initial dosage of 10-15 mg/day and a maximum of 30 mg/day.
For Bipolar mania in adults: In case of Generic Abilify Monotherapy the initial dosage is 15 mg/day, the recommended dosage is 15 mg/day and the maximum dosage 30 mg/day. In case Generic Abilify tablets are used as an adjunct to lithium or valproate the initial dose is 10-15 mg/day, the recommended dose is 15 mg/day with the maximum dose being 30 mg/day
The recommended dosage of Aripiprazole Tablets for the treatment of major depressive disorder in adults as an adjunct to antidepressants is 5-10 mg/day with the starting dose as 2-5 mg/day and the maximum dose being 15 mg/day.

Side Effects of Abilify Tablets

The most common side effects reported in patients treated with with an incidence rate of 5% or more and at least twice that for placebo:
Adult patients with schizophrenia: akathisia
Adult patients (monotherapy) with bipolar mania: akathisia, sedation, restlessness, tremor, and extrapyramidal disorder
Adult patients (adjunctive therapy with lithium or valproate) with bipolar mania: akathisia, insomnia, and extrapyramidal disorder
Adult patients with major depressive disorder (adjunctive treatment to antidepressant therapy): akathisia, restlessness, insomnia, constipation, fatigue and blurred vision
Adult patients with agitation associated with schizophrenia or bipolar mania: nausea

Generic Abilify Tablets - More Details

For more details on Generic please read the Prescription Information or watch the presentation below:

Tuesday 14 October 2014

Treatment of Osteoporosis and Paget's Disease using Generic Fosamax Tablets

What is osteoporosis?

Osteoporosis is a disease of bones which causes bones to become more porous, gradually making them weaker, more brittle and leads to an increased risk of fracture. Osteoporosis is common in postmenopausal women and also may occur in men. Osteoporosis often occurs in women several years after, the menopause, which occurs when the ovaries virtually stop producing the female hormone, oestrogen, or are removed (which may occur, for example, at the time of a hysterectomy). The earlier a woman reaches the menopause, the greater the risk of osteoporosis.
As many as half of all women and a quarter of men older than 50 will break a bone due to osteoporosis.
In osteoporosis, the bone mineral density (BMD) is reduced, bone microarchitecture deteriorates, and the amount and variety of proteins in bone are altered. Although Osteoporosis itself has no symptoms, its main consequence is the increased risk of bone fractures. Osteoporotic fractures occur in situations where healthy people would not normally break a bone; they are therefore regarded as fragility fractures.

What is Paget's Disease?

Paget's disease of bone is a disease that can result in enlarged and misshapen bones. In people with Paget's disease, there is excessive breakdown of bone tissue, and formation of new bone tissue causing the affected bone to weaken, resulting in pain, misshapen bones, fractures, and arthritis in the joints near the affected bones.
Paget's disease typically is localized, affecting just one or a few bones, as opposed to osteoporosis, for example, which usually affects all the bones in the body. It often involves bones of the arms, collarbones, leg, pelvis, spine, and skull.The disease occurs worldwide, but is more common in Europe, Australia, and New Zealand.

Generic Fosamax (Osteofos Tablets) – Product Information

Generic Fosamax (Osteofos Tablets) is used to prevent osteoporosis in postmenopausal women, and to treat Paget's disease of the bone. Generic Fosamax is also used to treat or prevent osteoporosis in men, premenopausal women and postmenopausal women using oestrogen who are receiving corticosteroid medicines, such as prednisone and dexamethasone.

Generic Fosamax Tablets - Contraindications

Generic Fosamax (Osteofos Tablets) are contraindicated in patients that have a hypersensitivity to Alendronate Sodium tor any inactive component of this medication. They are also contraindicated in patients that have Hypocalcaemia or abnormalities of the oesophagus which delay oesophageal emptying such as stricture or achalasia.
Osteofos Tablets should not be administered to patients that are unable to stand or sit upright for at least 30 minutes.

Generic Fosamax (Osteofos Tablets) - Dosage

Generic Fosamax must be taken at least one half hour before the first food, beverage, or medication of the day with plain water only. To reduce the chances of oesophageal irritation, Generic Fosamax should only be swallowed upon arising for the day with a full glass of water and patients should not lie down for at least 30 minutes and until after their first food of the day. The recommended dosage of for various indications is given below:
Treatment of Osteoporosis in Postmenopausal Women and in Men :
The recommended dosage is one 70 mg tablet once weekly.
Prevention of Osteoporosis in Postmenopausal Women:
The recommended dosage is 5 mg once a day.
Treatment and Prevention of Glucocorticoid-Induced Osteoporosis in Men, Premenopausal Women and Postmenopausal Women Receiving Oestrogen :
The recommended dosage is 5 mg once a day.
Paget's Disease of Bone in men and women : The recommended treatment regimen is 40 mg once a day for six months.

Side Effects of Generic Fosamax Tablets

The following upper gastrointestinal side effects were reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: abdominal pain, dyspepsia, oesophageal ulcer, dysphagia and abdominal distention. Rarely, rash and erythema have occurred. Additionally, the following side effects were also reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: musculoskeletal (bone, muscle or joint) pain, constipation, diarrhoea, flatulence, and headache.

Generic Fosamax Tablets - More Details

For more details please watch the presentation below:

Monday 13 October 2014

Generic Cipro for Treatment of Bacterial Infections

Generic Cipro (Ciplox Tablets) - Product Information

The active ingredient present in Generic Cipro (Ciplox Tablets) is ciprofloxacin hydrochloride. Ciplox Tablets are available in strengths of 100 mg, 250 mg, 500 mg and 750 mg. Generic Cipro (Ciplox Tablets) are used to treat infections caused by susceptible bacteria.

Uses of Generic Cipro (Ciplox Tablets)

Generic Cipro (Ciplox Tablets) - Dosage

Ciplox Tablets (Ciprofloxacin Hydrochloride) Dosage Ciplox tablets should be swallowed whole with adequate amount of liquid. Ciplox tablets can be taken with or without regard to meals. Fluids should be taken liberally. Antacids should not be taken concomitantly or within two hours of dosing. The adult dosage for various indications is given below: Respiratory tract, bone and joint infections:
Mild/moderate 500 mg twice daily/or 1000 mg once daily
Severe/complicated 750 mg twice daily
Urinary tract infections:
Acute uncomplicated 500 mg once daily for 3 days
Mild/moderate 250 mg twice daily / 500 mg once daily
Severe/complicated 500 mg twice daily/or 1000 mg once daily
Infectious diarrhoea:
Mild/moderate/severe 500 mg twice daily/or 1000 mg once daily
Gonorrhoea 250 mg single dose
Non-gonococcal urethritis 750 mg twice daily
Chancroid 500 mg twice daily/1000 mg once daily
Other infections 500-750 mg twice daily
Chronic Bacterial prostatitis:
1000 mg once daily for 28 days

Overdose Symptoms and Treatment

In the event of acute overdosage, reversible renal toxicity has been reported in certain cases. The stomach should be emptied by inducing vomiting or by gastric lavage. The patient should be carefully monitored and given supportive treatment, including monitoring of renal function and administration of magnesium, aluminum, or calcium containing antacids which can reduce the absorption of ciprofloxacin. Adeguate hydration must be maintained. Only a small amount of ciprofloxacin (< 10%) is removed from the body after hemodialysis or peritoneal dialysis.

Side Effects

The common side effects of Generic Cipro are Diarrhoea, vomiting, abdominal pain, headache, restlessness and rash

Generic Cipro - More Details

For more details please watch the presentation below:

Friday 10 October 2014

Treatment of Depression Using Generic Pamelor

What is Depression?

According to MediLexicon's Medical Dictionary, depression is "a mental state or chronic mental disorder characterized by feelings of sadness, loneliness, despair, low self-esteem, and self-reproach; accompanying signs include psychomotor retardation (or less frequently agitation), withdrawal from social contact, and vegetative states such as loss of appetite and insomnia."
Depressed people may feel sad, anxious, empty, hopeless, worried, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable; experience loss of appetite or overeating, have problems concentrating, remembering details, or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.
There are several types of depression(depressive disorders). Among the common types of depression are Major Depressive Disorder (major depression) and Dysthymic Disorder (dysthymia). Other types of depression include Psychotic depression, Postpartum depression (postnatal depression), SAD (seasonal affective disorder) and Bipolar disorder (manic-depressive illness).

Generic Pamelor – Product Information

Generic Pamelor (Primox Tablets / Sensival Tablets) is used for the relief of symptoms of depression. Nortriptyline Hydrochloride is also used for the treatment of nicotine dependence as an aid to smoking cessation.
Depression is thought to be caused by a chemical imbalance in parts of the brain. This affects your whole body and can cause emotional and physical symptoms such as feeling low in spirit, loss of interest in activities, being unable to enjoy life, poor appetite or overeating, disturbed sleep, often waking up early, loss of sex drive, lack of energy and feeling guilty over nothing. Generic Pamelor works by correcting this chemical imbalance and helps relieve the symptoms of depression.

Generic Pamelor - Active Ingredient

The active ingredient present in Generic Pamelor is Nortriptyline Hydrochloride.

Generic Pamelor - Contraindications

Generic Pamelor (Nortriptyline Hydrochloride) is contraindicated in the following situations:

  • Patients hypersensitive to nortriptyline hydrochloride or any inactive ingredient in the product should not be given the medication.
  • Cross-sensitivity between nortriptyline hydrochloride and other dibenzazepines is a possibility.
  • Nortriptyline is contraindicated for the treatment of nocturnal enuresis.
  • Nortriptyline Hydrochloride is contraindicated during the acute recovery period after myocardial infarction.
  • The concurrent use of nortriptyline hydrochloride or other tricyclic antidepressants with a monoamine oxidase inhibitor (MAOI) is contraindicated. It is advisable to discontinue the MAOI for at least 2 weeks before treatment with nortriptyline hydrochloride is started.
  • Nortriptyline is contraindicated for the treatment of depression in patients 12 years of age and under.

Generic Pamelor - Dosage

For the Relief of Symptoms of Depression:
Usual Adult Dose:
25 mg 3 or 4 times daily; dosage should begin at a low level and be increased as required.Doses above 100 mg per day are not recommended.
Elderly Patients:
25 mg to 50 mg per day, in divided doses.
Adolescent Depression:
Not recommended for use in adolescent patients 13-18 years of age for the treatment of depression, unless under the supervision of a specialist.
As an Aid in Smoking Cessation:
Nortriptyline hydrochloride is administered orally in the form of tablets. Commence dosing prior to quit date at 25 mg/day and then increase to 75 – 100mg when feasible over 10 days – 5 weeks. The recommended starting time is 10 – 28 days prior to the quit date and gradually increase to achieve a maintenance dose of 75 – 100 mg/day when possible for a total of up to 12 weeks.

Side Effects of Generic Pamelor

The common side effects of Generic Pamelor tablets are Stomach or bowel problems (e.g. nausea, diarrhoea, constipation), Dry mouth or taste change, Change in appetite, Shakiness or tremor, Trouble sleeping, Dizziness or light-headedness (especially on standing rapidly), Tingling or numbness of the hands or feet, Ringing or other persistent noise in the ears, and Difficulty in passing urine.
Inform your doctor as soon as possible if you notice any of the following as these side effects may be serious: Changes in the speed of your heart rate (increase or decrease), irregular heart beat, Agitation, anxiety, worsening of depression, Confusion or hallucinations (seeing or hearing things that are not there), Vision problems and Yellowing of the eyes or skin (jaundice).The above side effects are rare.
Inform your doctor immediately or go to accident and emergency at your nearest hospital if you notice any of the following very serious side effects:Symptoms of an allergic reaction (symptoms include: swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing), Severe chest pain or tightness, Thoughts of suicide, Fainting, seizures or fits. You may need urgent medical attention or hospitalisation. These side effects are very rare.

Generic Pamelor - More Details

For more details please watch the presentation below:

Thursday 9 October 2014

Treatment of Obesity using Generic Xenical Capsules

What is Obesity?

Obesity is a medical condition which is characterised by accumulatation of excess body fat has to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems. People are considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight in kilograms by the square of the person's height in metres, exceeds 30 kg/m2. In other words, a person is considered obese when his or her weight is 20% or more above normal weight.
Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity is most commonly caused by a combination of excessive food energy intake, lack of physical activity, and genetic susceptibility, although a few cases are caused primarily by genes, endocrine disorders, medications or psychiatric illness.

Generic Xenical Capsules (Orlimac Capsules) – Product Information

Generic Xenical (Orlimac Capsules) is a medicine used for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Generic Xenical is also used to reduce the risk for weight regain after prior weight loss.
The active ingredient present in Generic Xenical capsules is Orlistat. Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

Generic Xenical (Orlimac Capsules) - Contraindications

Generic Xenical (Orlimac Capsules) is contraindicated in patients with

  • A known hypersensitivity to Orlistat or to any component of this medication
  • Pregnancy
  • Patients with chronic malabsorption syndrome
  • Patients with cholestasis

Generic Xenical (Orlimac Capsules) - Dosage

The recommended adult Oral dosage of Generic Xenical (Orlistat Capsules) is one 120 mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal).
The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. If a meal is occasionally missed or contains no fat, the dose of Generic Xenical can be omitted. Patients should take a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat and distribute the daily intake of fat, carbohydrate, and protein over three main meals.

Side Effects of Generic Xenical (Orlimac Capsules)

The most common side effects reported in patients treated with Generic Xenical (Orlimac Capsules) are Gastrointestinal (GI) symptoms like Oily Spotting, Flatus with Discharge, Fecal Urgency, Fatty/Oily Stool, Oily Evacuation, Increased Defecation and Fecal Incontinence

Generic Xenical (Orlimac Capsules) - More Details

For more details please read the Prescription Information or watch the presentation below:

Wednesday 8 October 2014

Treatment of Hyperprolactinemic Disorders using Generic Dostinex

What are Hyperprolactinemic Disorders?

The medical condition which shows the presence of abnormally-high levels of prolactin in the blood is referred to as Hyperprolactinaemia or hyperprolactinemia (HP).
High levels of prolactin are associated with abnormal menstrual cycles in females and gonadal disorders in males. Hypogonadism is commonly associated with hyperprolactinemia and can cause many of the symptoms associated with raised prolactin levels. These symptoms can include oligomenorrhea (infrequent menstruation with markedly diminished menstrual flow) or amenorrhea (lack of menstrual cycles), and/or galactorrhea (excessive or spontaneous secretion of milk). Other symptoms of hyperprolactinemia in women can include decreased libido, hirsutism (condition of abnormal hairiness), acne, infertility, habitual abortion, and osteopenia. Infertility due to hyperprolactinemia is most often caused by chronic anovulation, defective folliculogenesis, and luteal phase inadequacy.
In men, the most common symptoms of hyperprolactinaemia are decreased libido, erectile dysfunction, infertility and gynaecomastia.

Generic Dostinex Tablets – Product Information

Generic Dostinex Tablets are prescribed to reduce your body’s level of a hormone known as prolactin. Generic Dostinex is used for the treatment of dysfunctions associated with hyperprolactinaemia, including amenorrhoea, oligomenorrhoea, anovulation and galactorrhoea. Cabgolin is also indicated in patients with prolactin-secreting pituitary adenomas. Generic Dostinex (Cabgolin Tablets) can also be prescribed to prevent the production of milk in women after birth, if breast-feeding is to be prevented for medical reasons. Generic Dostinex suppresses physiological lactation by inhibiting prolactin secretion.

Generic Dostinex (Cabgolin Tablets) - Active Ingredient

The active ingredient present in Generic Dostinex (Cabgolin Tablets) is Cabergoline.

Generic Dostinex (Cabgolin Tablets) - Contraindications

Generic Dostinex is contraindicated in patients that have hypersensitivity to cabergoline or any inactive component of this medicine or any ergot alkaloid. It is also contrindicated in patients with a history of pulmonary, pericardial and retroperitoneal fibrotic disorders. Anatomical evidence of cardiac valvulopathy of any valve as determined by pre-treatment echocardiogram showing valve leaflet thickening, valve restriction, valve mixed restriction-stenosis.

Generic Dostinex (Cabgolin Tablets) - Dosage

The recommended dosage of for various indications is given below:
Treatment of Hyperprolactinaemic Disorders:
To treat high levels of prolactin (hyperprolactinaemia), the recommended starting dose is 0.25mg taken twice a week.The weekly dose should be increased gradually preferably by adding 0.5mg per week at monthly intervals until the optimal therapeutic response is achieved.
Inhibition of Lactation:
To prevent the production of milk, the recommended dose is 1mg (two 0.5mg tablets) as a single dose taken once, on the first day after delivery.

Side Effects of Generic Dostinex (Cabgolin Tablets)

The most frequently occurring side effects include dizziness/vertigo, headache, pain in the stomach, nausea and abdominal pain or heartburn. Rarely occuring side effects were palpitations, epigastric pain, somnolence, epistaxis and transient hemianopsia, vomiting, syncope, asthenia, and hot flushes were reported.Most side effects were transient and mild to moderate in severity.

Generic Dostinex - More Details

For more details please read the prescription information or watch the presentation below:

Tuesday 7 October 2014

Migraine Headache Relief using Generic Imitrex

What is a Migraine Headache?

Migraine is a chronic disorder that is thought to involve abnormal functioning of the brain's blood vessels.Migraines cause severe pain on one or both sides of the head, upset stomach, nausea, and, at times, disturbed vision. Persons who have experienced migraines have described migraine pain as pulsing or throbbing in one area of the head. During migraines, people become very sensitive to light and sound.

Generic Imitrex Tablets - Product Information

Generic Imitrex (Suminat tablets manufactured by Sun Pharma) are used for the acute relief of migraine attacks with or without aura. Generic Imitrex tablets should not be used for prevention of migraine headaches.

Dosage and Administration

The recommended adult dose of oral Imitrex is a single 50mg tablet which has to be administered as early as possible after the onset of a migraine headache. Some patients may require 100 mg. A second dose should only be considered if some response to the first dose was observed. The doses should be by separated by at least 2 hours. The maximum dosage in a 24-hour period is 200 mg.
The maximum single dose in patients with mild to moderate hepatic impairment should not exceed 50 mg. It is equally effective irrespective of the stage of the migraine attack. The tablets should be swallowed whole with water. Do not crush or chew the tablet.

Generic Imitrex Tablets - Contraindications

Generic Imitrex (Suminat Tablets) are contraindicated in persons that have a hypersensitivity to Sumatriptan Succinate or any other component of the medicine. Imitrex Tablets should not be given to patients with history, symptoms, or signs of ischemic cardiac, cerebrovascular, or peripheral vascular syndromes. In addition, patients with other significant underlying cardiovascular diseases should not be administered Imitrex Tablets. Imitrex Tablets are also contraindicated in patients with severe hepatic impairment.

Side Effects of Generic Imitrex Tablets

The common side effects of Generic Imitrex (Suminat Tablets) are dyspnoea, nausea, vomiting, feeling of sleepiness, dizziness or tiredness, sensations of heaviness, feelings of weakness, fatigue, pain, tingling, heat or flushing in any part of the body, sensations of heat or cold, pressure or tightness, problems with your eyesight, feeling of faintness or "pass out", shaking or tremors and shortness of breath.
Tell your doctor immediately if you experience any of the following serious side effects after taking Generic Imitrex:
feel heaviness, pressure or tightness in any part of the body including the chest or throat
feel irregular heartbeats - too fast or too slow
have a fit or convulsion
have wheezing, swelling of the lips or mouth, difficulty in breathing, hayfever, lumpy rash ("hives") or fainting.
These side effects are likely to be serious. Stop taking Generic Imitrex (Suminat Tablets) and seek medical attention immediately.

Generic Imitrex Tablets - More Details

For more details please refer to the prescription information or watch the presentation below:

Thursday 2 October 2014

Treatment of GERD, Gastric & Duodenal Ulcer With Generic Prilosec

Generic Prilosec (Omez Capsules) – Product Information

Generic Prilosec (Omez Capsules) is a medicine which is a proton pump inhibitor. It is used in the treatment of dyspepsia, peptic ulcer disease (PUD) (Gastric and Duodenal), gastroesophageal reflux disease (GORD/GERD), laryngopharyngeal reflux (LPR) and Zollinger-Ellison syndrome. Generic Prilosec (Omez Capsules, manufactured by Dr. Reddy's Laboratories Ltd.) is available in tablets of 10 mg, 20 mg and 40 mg.

Generic Prilosec (Omez Capsules) - Indications

Generic Prilosec is used to treat the symptoms of reflux oesophagitis or reflux disease (GERD) in adults and in children. This can be caused by "washing back" (reflux) of food and acid from the stomach into the oesophagus(food pipe). Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn, which usually occurs after eating or at night and which worsens when bending over. Omeprazole is also used to treat acid-related dyspepsia and peptic ulcers. Depending on the position of the ulcer it is called a gastric or duodenal ulcer. Peptic Ulcers Associated with Helicobacter pylori Infection are treated with a combination of Generic Prilosec and antibiotics. When Generic Prilosec is taken together with two antibiotics, they are more effective than taken one or two at a time. Generic Prilosec is also used to heal and prevent ulcers associated with non-steroidal anti-inflammatory drugs (NSAIDs) which are commonly taken to relieve pain, swelling and other symptoms of inflammation, including arthritis. Generic Prilosec is also used to treat a rare condition called Zollinger-Ellison syndrome, where the stomach produces large amounts of acid, much more than in ulcers or reflux disease.

Generic Prilosec (Omez Capsules) - Contraindications

Generic Prilosec (Omez Capsules) is contraindicated in patients that have hypersensitivity to Omeprazole Magnesium or any inactive component of this medicine.

Generic Prilosec (Omez Capsules) - Dosage

Swallow Omeprazole capsules whole with a glass of water. Do not crush or chew. The recommended dosage of for various indications is given below:
Short-Term Treatment of Active Duodenal Ulcer:
The recommended dosage is 20 mg Once daily for 4 weeks. Some patients may require an additional 4 weeks Gastric Ulcer:
The recommended dosage is 40 mg Once daily for 4 to 8 weeks H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence:
Triple Therapy: consisting of a combination of Prilosec 20 mg, Amoxicillin 1000 mg and Clarithromycin 500 mg. Each medicine twice daily for 10 days
Dual Therapy: Prilosec 40 mg Once daily for 14 days and Clarithromycin 500 mg Three times daily for 14 days
GERD:
The recommended dosage is 20 mg Once daily for 4 to 8 weeks
Maintenance of Healing of Erosive Esophagitis:
The recommended dosage is 20 mg Once daily
Pathological Hypersecretory Conditions:
The recommended dosage is 60 mg Once daily (varies with individual patient)

Generic Prilosec (Omez Capsules) - Missed Dose

If you forget to take a dose, take it as soon as you remember, and then go back to taking it as you would normally. If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Do not take a double dose to make up for the dose that you missed.

Side Effects of Generic Prilosec (Omez Capsules)

The side effects of Generic Prilosec (Omez Capsules) Tablets include diarrhoea, wind (flatulence) or constipation, nausea and/or vomiting, stomach pain or discomfort,dry mouth, skin rash, itching, headache and/or dizziness, breast enlargement in men and unusual hair loss or thinning.
Inform your doctor as soon as possible in case you notice any of the following:

  • Muscle pain or weakness, joint pain
  • "Pins and needles" (tingling or numbness of the hands and feet)
  • Changes in sleep patterns
  • changes in mood
  • Hallucinations or confusion
  • Bleeding or bruising more easily than normal, nose bleeds
  • Frequent infections such as fever, severe chills, sore throat or mouth ulcers
In case you notice any of the very rare but very serious side effects below, inform your doctor immediately or go to Accident and Emergency at the nearest hospital
  • Severe skin reaction which may include redness, blistering and peeling of the skin, accompanied with fever and chills, aching muscles
  • Ulcers, blisters or bleeding of the lips, eyes, mouth, nose and genitals
  • Swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.

Generic Prilosec (Omez Capsules) - More Details

For more details please read the prescription information or watch the presentation below: