Postoperative Nausea and Vomiting
According to the latest figures available, Postoperative Nausea and Vomiting (PONV) occurs in an estimated to be 25 to 30%, with severe, intractable PONV estimated to occur in approximately 0.18% of all patients undergoing surgery. PONV can lead to delayed recovery room discharge and unanticipated hospital admission, thereby increasing medical costs and causing a delay in returning to normal activities. The recently introduced class of antiemetics used for the prevention and treatment of PONV are the serotonin receptor antagonists like Ondansetron Hydrochloride (Generic Zofran Tablets) do not have the adverse effects of the older, traditional medicines used against vomiting and nausea. Headache and dizziness are the main side effects of these medications in the dosages used for PONV.
Causes of Postoperative Nausea and Vomiting (PONV)
Postoperative nausea and vomiting results from anaesthesic, surgical, and patients factors. It has been observed that Gynaecological, urological, strabismus correction and middle ear surgery have a higher risk of PONV.
Generic Zofran Tablets – Product Information
Postoperative nausea and vomiting can be prevented by administering Generic Zofran (Emeset Tablets) one hour prior to anaesthesia. Generic Zofran Tablets are also used for the prevention of nausea and vomiting that may be caused by chemotherapy and radiotherapy treatments. The active ingredient in Generic Zofran (Emeset Tablets) is ondansetron hydrochloride Dihydrate. Generic Zofran is available in tablets of 4 mg and 8 mg.
Generic Zofran (Emeset Tablets) - Contraindications
Generic Zofran is contraindicated in patients that have hypersensitivity (e.g., anaphylaxis) to ondansetron hydrochloride or any inactive component of this medicine. Concomitant use of Generic Zofran with apomorphine is also contraindicated.
Generic Zofran Tablets - Dosage
The recommended dosage of Generic Zofran for various indications is given below:
Emetogenic Chemotherapy and Radiotherapy:
The recommended oral dose of is 8 mg one to two hours before treatment, followed by 8 mg orally 12 hours later. The recommended oral dose is 8 mg to be taken twice daily. To protect against delayed or prolonged emesis after the first 24 hours, oral treatment with Ondansetron should be continued for up to 5 days after a course of treatment.
Post-Operative Nausea and Vomiting:
For prevention of post-operative nausea and vomiting, the recommended oral dose is 16 mg given one hour prior to anaesthesia.
Side Effects of Generic Zofran (Emeset Tablets)
The most common side effects of Generic Zofran in adults are diarrhea, headache, a sensation of warmth or flushing, constipation, hiccups and fever. These are all mild side effects.
Generic Zofran Tablets - More Details
For more details please read the prescription information or watch the presentation below:
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