What is Secondary Amenorrhea?
Secondary amenorrhea occurs when a woman who has been having normal menstrual cycles stops getting her periods for 6 or more months in a woman with previously normal menstruation. Secondary amenorrhoea (menstruation cycles ceasing) is often caused by hormonal disturbances from the hypothalamus and the pituitary gland, from premature menopause or intrauterine scar formation.
What is Abnormal Uterine Bleeding?
Abnormal bleeding from the uterus where the lining of the uterus breaks down during the menstrual cycle rather than at the end resulting in vaginal spotting or bleeding.
Dysfunctional uterine bleeding (DUB), defined as abnormal uterine bleeding not caused by pelvic pathology, medications, systemic disease or pregnancy, is the most common cause of abnormal uterine bleeding.
What is Endometrial Hyperplasia?
Endometrial Hyperplasia or Endometriosis is defined as the condition in which tissue similar to the lining of the uterus (womb) grows outside the uterus, causing pain and bleeding.
Most cases of endometrial hyperplasia result from high levels of estrogens, combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this tissue.
Generic Provera (Deviry Tablets) – Product Information
Generic Provera Tablets (Deviry Tablets) is a progestin indicated for the treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as fibroids or uterine cancer.
Deviry Tablets is also indicated to reduce the incidence of endometrial hyperplasia in nonhysterectomized postmenopausal women receiving daily oral conjugated estrogens. Each 10 mg Generic Provera tablet for oral administration contains 10 mg of Medroxyprogesterone Acetate.
Generic Provera Tablets - Contraindications
Generic Provera should not be used in women with any of the following conditions:
1. Undiagnosed abnormal genital bleeding
2. Known, suspected, or history of cancer of the breast
3. Known or suspected estrogen- or progesterone-dependent neoplasia
4. Active deep vein thrombosis, pulmonary embolism or a history of these conditions
5. Active or recent (within the past year) arterial thromboembolic disease (for example,
stroke and myocardial infarction)
6. Known liver dysfunction or disease
7. Missed abortion
8. As a diagnostic test for pregnancy
9. Known hypersensitivity to the Medroxyprogesterone Acetate or any inactive ingredient present in the medicine.
10. Known or suspected pregnancy.
Generic Provera (Deviry Tablets) - Dosage
The recommended Dosages for Generic Provera are as follows:
Absence of menstrual period:
Generic Provera may be given in doses ranging from 5 to 10 mg daily for 5 to 10 days.
Abnormal Uterine Bleeding:
Generic Provera may be given in doses ranging from 5 to 10 mg daily for 5 to 10 days.
Overgrowth of the lining of the uterus:
When used in combination with oral conjugated estrogens in postmenopausal women with a uterus, Generic Provera may be given in doses ranging from 5 or 10 mg daily for 12 to 14 straight days per month.
Side Effects of Generic Provera Tablets
The following side effects have been reported in women taking progestins, including Generic Provera Tablets, without concomitant estrogens treatment:
Abnormal uterine bleeding (irregular, increase, decrease), change in menstrual flow, breakthrough bleeding, spotting, amenorrhea, changes in cervical erosion, cervical secretions, Breast tenderness, mastodynia or galactorrhea.
Thromboembolic disorders including thrombophlebitis and pulmonary embolism, Nausea, cholestatic jaundice, Skin Sensitivity reactions consisting of urticaria, pruritus, edema and generalized rash, Acne, alopecia and hirsutism, Neuro-ocular lesions, for example, retinal thrombosis, and optic neuritis, Mental depression, insomnia, somnolence, dizziness, headache, nervousness, Hypersensitivity reactions, rash (allergic) with and without pruritus, change in weight (increase or decrease), pyrexia, edema/fluid retention, fatigue and decreased glucose tolerance.
Generic Provera Tablets - More Details
For more details please read the prescription information or watch the presentation below:
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