Treatment of Duodenal and Gastric Ulcers Using Generic Zantac Tablets

What are Peptic Ulcers?

If a breakdown of the protective lining of of the stomach or the first part of the small intestine (duodenum) occurs it causes inflammation, which is termed as a Peptic Ulcer. A peptic ulcer in the stomach is called a gastric ulcer, whereas an ulcer in the duodenum is called a duodenal ulcer. It is defined as mucosal erosions equal to or greater than 0.5 cm.
Symptoms of a peptic ulcer can include abdominal pain, bloating and abdominal fullness, waterbrash(rush of saliva after an episode of regurgitation to dilute the acid in esophagus), nausea, and copious vomiting, loss of appetite and weight loss, hematemesis (vomiting of blood) and melena (tarry, foul-smelling feces due to oxidized iron from hemoglobin). On rare occassions, an ulcer can lead to a gastric or duodenal perforation, which leads to acute peritonitis and is extremely painful. Immediate surgery is required to treat a Duodenal perforation

Causes of Peptic Ulcers

A major causative factor (60% of gastric and up to 90% of duodenal ulcers) of Peptic Ulcers is chronic inflammation caused by bacteria called Helicobacter pylori that colonizes the antral mucosa. The immune system is unable to clear the infection, despite the appearance of antibodies. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Generic Zantac Tablets – Product Information

Generic Zantac (Zinetac Tablets) is used in treatment of peptic ulcers (gastric and duodenal ulcers), Gastroesophageal Reflux Disease (GERD), Zollinger-Ellison syndrome and scleroderma oesophagitis and to prevent duodenal ulcers and reflux disease from recurring. The active ingredient in Generic Zantac (Zinetac Tablets) is Ranitidine Hydrochloride. Generic Zantac (Zinetac Tablets) is available in tablets of 150 mg and 300 mg. Each Generic Zantac 150 Tablet for oral administration contains 168 mg of Ranitidine HCl equivalent to 150 mg of ranitidine.

Generic Zantac (Zinetac Tablets) - Contraindications

Generic Zantac is contraindicated in patients that have hypersensitivity to Ranitidine Hydrochloride or any inactive component of this medicine.

Generic Zantac Tablets - Dosage

The recommended dosage of Generic Zantac for various indications is given below:
Active Duodenal Ulcer: The recommended adult oral dosage of Generic Zantac for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The current recommended adult oral dosage is 150 mg twice daily.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice daily.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice daily.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg or 10 mL of syrup 4 times daily.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice daily.

Side Effects of Generic Zantac (Zinetac Tablets)

The side effects of Generic Zantac Tablets include headache, tiredness, dizziness, joint or muscle pains, diarrhoea, constipation, nausea (feeling sick), vomiting, stomach cramps or pain, sleeping problems, hair loss, decreased sex drive, impotence, abnormal uncontrolled movements, muscle twitching or spasms.Inform your doctor immediately if you notice any of the following serious side effects:

• yellowing of the skin or eyes
• depression, confusion, hallucinations
• fast, slow or irregular heartbeat
• severe upper stomach pain together with nausea or vomiting
• signs of frequent infections such as fevers, chills, sore throat or mouth ulcers
• bruising or bleeding more easily than normal
• general ill health associated with weight loss
• fever
• skin rash, redness, itching.

In case any of the following rare side effects occur, stop taking the medication tell your doctor immediately, or go to Accident and Emergency at the nearest hospital:

• hives or severe skin reactions
• swelling of the face, mouth, throat or limbs
• chest tightness, shortness of breath or difficulty breathing.

Generic Generic Zantac - More Details

For more details please read the prescription information or watch the presentation below:

Treatment of Myasthenia Gravis, Paralytic Ileus & Postoperative Urinary Retention using Generic Mestinon

What is Myasthenia Gravis?

Myasthenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigability. An autoimmune disorder occurs when the body's immune system mistakenly attacks healthy tissue. In people who suffer from myasthemia gravis, the body produces antibodies that block the muscle cells from receiving messages (neurotransmitters) from the nerve cell.
The external symptoms of myasthenia gravis is fatigability. Muscles become progressively weaker during periods of activity and improve after periods of rest. Muscles that control eye and eyelid movement, facial expressions, chewing, talking, and swallowing are especially susceptible. The muscles that control breathing and neck and limb movements can also be affected. Often, the physical examination yields results within normal limits.

Generic Mestinon (Distinon Tablets) – Product Information

Generic Mestinon (Distinon Tablets, manufactured by Samarth Pharma) is used to treat muscle weakness in people with myasthenia gravis, and to combat the effects of curariform drug toxicity. It is also used to treat paralytic ileus, postoperative urinary retention and orthostatic hypotension.

Generic Mestinon (Distinon Tablets) - Contraindications

Generic Mestinon are contraindicated in patients that have a hypersensitivity to Pyridostigmine Bromide or any inactive component of this medication. They are also contraindicated in the following cases:
Generic Mestinon should not be given to patients with mechanical gastrointestinal or urinary obstruction.
Generic Mestinon should not be used in conjunction with depolarising muscle relaxants such as suxamethonium as neuromuscular blockade may be potentiated and prolonged apnoea may result.

Generic Mestinon (Distinon Tablets) - Dosage

The dosage of Generic Mestinon for various indications is given below:
Myasthenia Gravis
Adults: Doses of 30 to 120 mg by mouth are given at intervals throughout the day when maximum strength is needed (for example on rising and before meal times). The usual duration of action of a dose is three to four hours.
Other indications:
The usual dose is 1 to 4 tablets of 60 mg by mouth

Side Effects of Generic Mestinon

The common side effects of Generic Mestinon tablets are nausea and vomiting, increased salivation, diarrhoea and abdominal cramps.

Generic Mestinon (Distinon Tablets) - Warnings and Precautions

The precautions to be taken when undergoing thereapy with Generic Mestinon are:
Hypersensitivity reactions may occur in susceptible individuals.
Extreme caution is required when administering Generic Mestinon to patients with bronchial asthma.
Care should be taken in patients with bradycardia, recent coronary occlusion, hypotension, vagotonia, epilepsy or Parkinsonism.
There is no evidence to suggest that Generic Mestinon has any special effects in the elderly. However, elderly patients may be more susceptible to dysrhythmias than the younger adult.
Generic Mestinon is mainly excreted unchanged by the kidney, therefore lower doses may be required in patients with renal disease and treatment should be based on titration of drug dosage to effect.
Generic Mestinon should not be given during cyclopropane or halothane anaesthesia; however, it may be used after withdrawal of these agents.

Generic Mestinon Tablets) - More Details

For more details please read the Prescription Information or watch the presentation below:

Treatment Of Genital Warts and Actinic Keratosis Using Generic Aldara Cream

Generic Aldara Cream (Imiquad 5% Cream) – Product Information

Generic Aldara Cream (Imiquad 5% Cream, manufactured by Gracewell) is an immune response modifier for topical administration. Generic Aldara Cream is used for the topical treatment of Clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses (AK) on the face or scalp in immunocompetent adults.
Biopsy-confirmed, primary superficial basal cell carcinoma (sBCC) in immunocompetent adults when surgical methods are medically less appropriate and patient follow-up can be reasonably assured.
External genital and perianal warts/condyloma acuminata in patients 12 years old or older.

Generic Aldara Cream - Active Ingredient

The active pharmaceutical ingredient present in Generic Aldara Cream is Imiquimod.
Each 0.25 gram single sachet of Imiquad Cream contains 12.5 mg of imiquimod in an off-white oil-in-water vanishing cream base.

Generic Aldara Cream (Imiquad 5% Cream) - Contraindications

Generic Aldara Cream is contraindicated in patients with the following conditions:

• Generic Aldara Cream is contraindicated in patients with hypersensitivity to imiquimod or inactive ingredients present in the cream.

Imiquad 5% Cream - Dosage

The dosage for various indications is given below:
Actinic keratosis: 2 times per week for a full 16 weeks
Superficial basal cell carcinoma: 5 times per week for a full 6 weeks.
External genital warts (EGW): 3 times per week until total clearance or a maximum of 16 weeks
Generic Aldara cream is to be applied prior to normal sleeping hours, and left on the skin for 6-10 hours. Hand washing before and after cream application is recommended.
Imiquimod 5% cream is packaged in single use packets which contain sufficient cream to cover an area of up to 20 cm2. A thin layer of the cream is applied to the affected area and rubbed in until the cream is no longer visible.

Side Effects of Generic Aldara Cream

The most common possible side effects reported in patients treated with Generic Aldara Cream with an incidence rate 28% or more are application site reactions or local skin reactions: itching, burning, erythema, flaking/scaling/dryness, scabbing/crusting, edema, induration, excoriation, erosion, ulceration.
The other reported Side Effects of Imiquad 5% Cream with Incidence rate 1% or more include fatigue, fever, and headache.

Generic Aldara Cream - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Aldara Cream for Genital Warts & Actinic Keratosis