What is Hormone Replacement Therapy (HRT)?
Hormone Replacement Therapy (HRT) is a medical treatment for surgically menopausal (after surgical removal of the ovaries), perimenopausal and postmenopausal women. This treatment prevents discomfort caused by diminished circulating estrogen and progesterone hormones, and in the case of the surgically or prematurely menopausal and may reduce incidence of dementia.
It involves the use of one or more of a group of medications called estrogens, progesterone or progestins designed to artificially boost hormone levels.
What does Progynova Do?
Progynova replaces the hormone oestradiol (Estradiol) that the body no longer makes and prevents or relieves symptoms such as hot flushes, sweats, sleep disturbances, depressive moods, irritability, dizziness, headaches as well as vaginal dryness and burning.
Progynova Tablets – Product Information
Progynova Tablets is used as Hormone replacement therapy (HRT) for the treatment of signs and symptoms of oestrogen deficiency due to the menopause.
Progynova Tablets is used to treat short term treatment of climacteric complaints after the cessation of monthly bleeding, or deficiency symptoms after oophorectomy or radiological castration for non-carcinomatous diseases, such as hot flushes, outbreaks of sweat, sleep disturbances, depressive moods, irritability, headaches, dizziness.
The active ingredient present in Progynova tablets is Estradiol Valerate (Oestradiol Valerate). Each 1mg tablet of Progynova contains 1 mg of Estradiol Valerate (Oestradiol Valerate).
Progynova Tablets - Contraindications
Progynova Tablets should not be used in women with any of the following conditions:
1.Pregnancy or lactation
2.Undiagnosed vaginal bleeding
3.Known or suspected cancer of the breast
4.Active deep vein thrombosis, thromboembolic disorders, thrombophlebitis or a documented history of these conditions
5.Active or recent (within the past year) arterial thromboembolic disease (for example, stroke and myocardial infarction)
6.Known or suspected premalignant conditions or malignancies, if sex steroid influenced
7.Presence or history of liver tumours (benign or malignant)
8.Severe hepatic disease
9.Known hypersensitivity to Estradiol Valerate (Oestradiol Valerate) or any inactive ingredient present in the medicine.
10.Hereditary or acquired predisposition to venous thrombosis (e.g. antithrombin III deficiency).
11.Severe hypertriglyceridamia.
12.A high risk of venous or arterial thrombosis.
Progynova Tablets (Estradiol Valerate) - Dosage
Hysterectomised patients may start at any time.If the patient is still menstruating and has an intact uterus, a combination regimen of Progynova and a progestogen should begin within the first 5 days of menstruation.
Patients whose periods are very infrequent or with amenorrhoea or who are postmenopausal may start at any time, provided pregnancy has been excluded.
The tablet should be taken at the same time of day every day. One tablet is taken daily. The tablets are to be swallowed whole with some liquid.
Side Effects of Progynova Tablets (Estradiol Valerate)
The common side effects of Progynova Tablets are Weight increase or Weight decrease, Headache, Abdominal pain, Nausea, Rash, Pruritus, Uterine/ Vaginal bleeding including spotting.
Uncommon side effects of Progynova Tablets include Hypersensitivity reaction, Depressed mood, Dizziness, Visual disturbances, Palpitations, Dyspepsia, Erythema nodosum, Urticaria, Breast pain, Breast tenderness and Oedema
Rarely occuring side effects of Progynova Tablets are Anxiety, Libido decreased or Libido increased, Migraine, Contact lens intolerance, Bloating, Vomiting, Hirsutism, Acne, Muscle cramps, Dysmenorrhoea, Vaginal discharge, Premenstrual-like syndrome, Breast enlargement, and Fatigue.
Inform your doctor immediately, or go to Accident and Emergency department at your nearest hospital if you notice any of the following:
Signs of allergy such as rash, swelling of the face, lips, mouth, throat or other parts of the body, shortness of breath, wheezing or trouble breathing, visual disturbances such as partial or complete loss of vision, bulging eyes, double
vision, irregular heartbeat or swelling of the hands, ankles or feet.
Progynova Tablets - More Details
For more details please read the prescription information or watch the presentation below:
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